Sanofi Pasteur Inc.

Sanofi Pasteur Sa

Scott Gallichan

Neil L Berinstein

Laszlo Radvanyi

Corey Lovitt

Devender Singh-Sandhu

Artur Pedyczak

Mark Parrington

Raymond P Oomen

Shi-Xian Cao

Jean Haensler

Martina Ochs-Onolemhemhen

Garry Morefield

Francois Dalencon

Kevin Harper

Belma Ljutic

Marie-Danielle Salha

Ausra Mancevski

Devender Satsangi Singh Sandhu

Nathalie Reveneau

Jin Su

Fernando Ausar

This disclosure relates to adjuvants for use in immunogenic compositions comprising at least one antigen and an aluminum compound comprising hydroxyl groups that has been treated with phosphate, carboxylate, carbonate, sulfate diphosphonate or a mixture of two or more of these compounds and methods of using these compositions for preventing and treating diseases are also provided.

Immunogenic compositions and related methods

The present invention provides compositions comprising a Chlamydial major outer membrane protein (referenced herein as 'MOMP'), from at least one Chlamydial serovar and an adjuvant, characterized in that the adjuvant comprises the product E6020 having CAS Number 287180-63-6. The composition may further comprise at least one carrier system (e.g., emulsion, mineral particle). The MOMP protein may be derived from any species of(e.g.,, orMoPn). In preferred embodiments, the composition comprises one or more major outer membrane proteins each derived from different serovars of. The invention also provides methods of inducing an immune response to aspecies (e.g.,) in a subject, by administering to the subject a composition of the invention.

Immunogenic compositions

The present invention relates to a nucleic acid encoding a polypeptide and the use of the nucleic acid or polypeptide in preventing and/or treating cancer. In particular, the invention relates to improved vectors for the insertion and expression of foreign genes encoding tumor antigens for use in immunotherapeutic treatment of cancer.

Tumor antigens BFA4 and BCY1 for prevention and / or treatment of cancer

The technology relates to monoclonal antibodies useful in the identification of cancer cells. In one embodiment, mAbs with specificity for tumor antigens are provided. In one embodiment, methods for treating cancer using mAbs are provided. In another embodiment, methods for detecting cancerous cells are provided. In another embodiment, kits for detecting cancerous cells are provided.

Monoclonal antibodies and uses thereof

Tumor antigens for prevention and/or treatment of cancer

The present invention relates to a nucleic acid encoding a polypeptide and the use of the nucleic acid or polypeptide in preventing and/or treating cancer. In particular, the invention relates to improved vectors for the insertion and expression of foreign genes encoding tumor antigens for use in immunotherapeutic treatment of cancer. 

Tumor antigens Bfa5 for prevention and/or treatment of cancer

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Campbellville, Canada

Scott Gallichan