Dow Agrosciences LLC

The Procter Gamble Company

Wisconsin Alumni Research Foundation

Scott B Bintrim

Scott Bevan

Patricia C Apel-Birkhold

Jon Christopher Mitchell

Donald J Merlo

Ignacio Mario Larrinua

Baolong Zhu

Lining Guo

Scott A Young

Barry W Schafer

Susan B Green

James A Strickland

Timothy Denver Hey

Thomas Meade

James K Petell

David J Bowen

Richard H Ffrench-Constant

Weiting W Ni

Jerald Coleman Ensign

Gregory L Orr

Todd A Ciche

Ze Sheng Li

Jennifer L Tenor

Amanda D Schleper

Shawn David McConaughy

Raymond Fatig

Adam Michael Pitz

Valerie Lynn Vanlandingham

Raymond O Fatig

Jon C Michell

Multi-use personal care compositions and articles can include a surfactant, a water insoluble hygroscopic fine, fiber, or filament, and a preservative, where such compositions and articles can show an improved preservative property versus unpreserved compositions.

Preserving personal care compositions

The subject invention relates to the surprising discovery that toxin complex (TC) proteins, obtainable from, and, can be used interchangeably with each other. In particularly preferred embodiments of the subject invention, the toxicity of a 'stand-alone' TC protein (from, or, for example) is enhanced by one or more TC protein 'potentiators' derived from a source organism of a different genus from which the toxin was derived. As one skilled in the art will recognize with the benefit of this disclosure, this has broad implications and expands the range of utility that individual types of TC proteins will now be recognized to have. Among the most important advantages is that one skilled in the art will now be able to use a single set of potentiators to enhance the activity of a stand-aloneprotein toxin as well as a stand-aloneprotein toxin. (As one skilled in the art knows,toxin proteins tend to be more desirable for controlling lepidopterans whiletoxin proteins tend to be more desirable for controlling coleopterans.) This reduces the number of genes, and transformation events, needed to be expressed by a transgenic plant to achieve effective control of a wider spectrum of target pests. Certain preferred combinations of heterologous TC proteins are also disclosed herein. Other objects, advantages, and features of the subject invention will be apparent to one skilled in the art having the benefit of the subject disclosure.

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The subject invention provides unique biological alternatives for pest control. More specifically, the present invention relates to novel pesticidal proteins, novel sources of pesticidal proteins, polynucleotides that encode such toxins, and to methods of using these toxins to control insects and other plant pests. The subject invention relates to the surprising discovery thatspecies, and proteins therefrom, have toxicity to lepidopterans. There have been no known reports of aspecies, strain, or protein having toxicity to lepidopterans. This is also the first known example of aCry protein that is toxic to lepidopterans. Furthermore, this is the first known report of ahaving toxin complex (TC)-like proteins. The DAS1529 isolate disclosed here is also the first known example of a natural bacterium that produces both a Cry toxin and TC proteins. The subject invention also relates to new classes of Cry and TC proteins that are pesticidally active.

The subject invention relates to noveltoxin complex (TC) proteins and genes that encode these proteins. More specifically, the subject invention relates to TC genes and proteins obtainable fromstrain Xwi. The subject invention also provides an exochitinase obtainable from the Xwi strain. This exochitinase can be used to control insects using methods known in the art.

The subject invention relates to the surprising discovery that toxin complex (TC) proteins, obtainable fromandcan be used interchangeably with each other. In particularly preferred embodiments of the subject invention, the toxicity of a 'stand-alone' TC protein (fromorfor example) is enhanced by one or more TC protein 'potentiators' derived from a source organism of a different genus from which the toxin was derived. As one skilled in the art will recognize with the benefit of this disclosure, this has broad implications and expands the range of utility that individual types of TC proteins will now be recognized to have. Among the most important advantages is that one skilled in the art will now be able to use a single set of potentiators to enhance the activity of a stand-aloneprotein toxin as well as a stand-aloneprotein toxin. (As one skilled in the art knows,toxin proteins tend to be more desirable for controlling lepidopterans whiletoxin proteins tend to be more desirable for controlling coleopterans.) This reduces the number of genes, and transformation events, needed to be expressed by a transgenic plant to achieve effective control of a wider spectrum of target pests. Certain preferred combinations of heterologous TC proteins are also disclosed herein. Other objects, advantages, and features of the subject invention will be apparent to one skilled in the art having the benefit of the subject disclosure.

Mixing and matching TC proteins for pest control

The subject invention relates to novel nucleic acid encoding astrain Xwi toxin complex (TC) protein and plants and bacteria transformed therewith.

Proteins from the genus Xenorhabdus are toxic to insects upon oral exposure. These protein toxins can be applied to insect larvae food and plants for insect control.

Insecticidal protein toxins from Xenorhabdus

Insecticidal protein toxins from xenorhabdus

Growing community of inventors

Westfield, IN, United States of America

Scott B Bintrim