Intel Corporation

Stc.unm

The University of New Mexico

Scott A Sibbett

Dimiter N Petsev

Plamen B Atanassov

Gabriel P Lopez

Carolin Lau

Gustavo Pio Marchesi Krall Ciniciato

A pliable pressure sensitive sensor device and method of making the same is provided. The sensor includes first and second pliable protective layers, which cover sets of conductive fibers that spatially separated by an electrically conductive pliable layer, which deforms in response to a pressure event. The fiber sets form a grid pattern and are in electrical communication with sets of electrical contacts located in predetermined locations along the fibers. In response to a pressure event in proximity to the contact, the pliable layer deforms and increases the amount of surface area in contact with an electrical contact whereby an electrical resistance at an individual electrical contact decreases in response to the pressure event.

Pliable pressure-sensing fabric

The present invention provides a semi-quantitative lateral flow assay device and method for generating semi-quantitative data from a lateral flow assay. The device comprises a thin, porous hydrophilic substrate wherein the substrate includes a star-shaped or other geometry taken in plan view having a liquid sample-receiving central region and multiple arms that extend or radiate out from the central region. Each arm includes a reaction zone formed by the presence of an analyte-capturing agent wherein the reaction zone of each arm is located at a different distance from the central region such that the analyte in the sample is captured accumulates in different quantities at at least some of the reaction zones of the arms in a manner that can be analyzed to yield semi-quantitative data from lateral flow assays. The reaction zones on the arms can be analyzed visually and/or by software analysis of a digital image based on color saturation, grayscale, or other characteristics of the reactions zones due to the presence of different amounts of analyte to produce semi-quantitative data of the total loading of a virus or other agent of interest of a patient's blood.

Semi-quantitative lateral flow assays

The present disclosure provides biological fuel cells comprising a paper-based fuel delivery layer which delivery fuel to the biological anode and cathode via capillary action and/or evaporation. In some embodiments the paper-based fuel delivery layer incorporates an outwardly extending fan-shaped region which enables a constant volumetric flow rate through the cell.

Paper-based fuel cell

Disclosed herein are an apparatus and a method for separating molecules on the basis of size and or structure, and to a method of making the apparatus. Generally, the separation method includes passing a fluid comprising particles having different effective molecular diameters through a plurality of open, nanoscale channels disposed in surfaces of substrates. The method also includes obtaining a plurality of fractions of the passed fluid such that each of the fractions includes a major portion containing particles having similar size and shape and substantially free of particles having larger size and shape. The apparatus includes first and second substrates each of which has a surface containing a plurality of open, nanoscale channels disposed therein. The surfaces are bonded together such that each of the channels of the first substrate is in fluid communication with at least two of the channels of the second substrate and is misaligned relative to the channels of the second substrate. Interferometric lithography and anodic bonding or flip-chip bonding techniques can be used to make the apparatus.

Sieving media from planar arrays of nanoscale grooves, method of making and method of using the same

A microfluidic device and method is disclosed having one or more membranes for the control of electrolysis. In one embodiment, a microfluidic device is disclosed that includes body with first channel and second channels separated by a gel layer. A first electrode positioned in the first channel and a second electrode positioned in the second channel wherein a potential applied to the first and second electrodes passes electrons from the first channel to the second channel through the gel layer. In another embodiment, a microfluidic device includes a body having a surface with a channel separating two first reservoirs. One or more membranes are positioned on the surface covering a portion of the channel and a blank is positioned covering the channel and the one or more membranes. A second reservoir through the blank is in contact with the membrane, each second reservoir in communication with the channel via the membrane. A first electrode is positioned in the first reservoir and a second electrode is positioned in the second reservoir wherein a potential applied to the first and second electrodes passes electrons from the first channel to the second channel through the membranes.

Fabrication and use of semipermeable membranes and gels for the control of electrolysis

Fabrication and use of semipermeable membranes and gels for the control of electrolysis in a microfluidic device

Charged particles may undergo two different separations within a single device, without manual intervention to effect the transfer of the particles between separations. In some embodiments, the device may be a Micro-Electro-Mechanical System.

Growing community of inventors

Corrales, NM, United States of America

Scott A Sibbett