Screen Holdings Co., Ltd.

Saya Shibata

Hiroshi Ogi

Tomoyasu Furuta

A threshold determination method includes a region specification step of specifying cell regions corresponding to individual cells in an image obtained by imaging the biological specimen, a determination step of setting temporarily a threshold for staining density quantitatively indicating the degree of staining of the cell region, comparing the staining density and the threshold for each of the cell regions and determining whether a stained state is positive or negative for staining, a receiving step of displaying a determination result of the stained state of each of the cell regions and receiving an operation input of a user to change the determination result for each cell region, and a resetting step of resetting the threshold in accordance with the determination result after change. It is possible to optimize effectively a threshold used in determining a stained state from an image of an immunohistostained specimen while human judgment is made.

Threshold determination method

An image display method according to this invention includes obtaining an image set including a plurality of stained images, the plurality of stained images being obtained by imaging a multiple immunostained tissue specimen, a registration processing being performed for mutual registration for the plurality of stained images, and switching and displaying the stained images included in the image set on a screen in accordance with a predetermined switch rule with a result of the registration processing reflected. An image includes at least one of the stained images and a graphical user interface for receiving an operation input from a user for editing the switch rule being displayed on the screen. The switch rule is changed and set according to the operation input. The image is displayed on the screen in accordance with the changed and set switch rule.

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Kyoto, Japan

Saya Shibata