The Brigham and Women's Hospital, Inc.

Leland Stanford Junior University

Beth Israel Deaconess Medical Center, Inc.

Savas Tasoglu

Utkan Demirci

Ronald W Davis

Lars Steinmetz

Naside Gozde Durmus

Ionita C Ghiran

Huseyin Cumhur Tekin

Hooman Safaee

Ionita Ghiran

Xiaohui Zhang

Magnetic cell levitation and cell monitoring systems and methods are disclosed. A method for separating a heterogeneous population of cells is performed by placing a microcapillary channel containing the heterogeneous population of cells in a magnetically-responsive medium in the disclosed levitation system and separating the cells by balancing magnetic and corrected gravitational forces on the individual cells. A levitation system is also disclosed, having a microscope on which the microcapillary channel is placed and a set of two magnets between which the microcapillary channel is placed. Additionally, a method for monitoring cellular processes in real-time using the levitation system is disclosed.

System and method for cell levitation and monitoring

In one aspect, the present disclosure provides a method for self-assembly of magnetic building blocks, including distributing a plurality of building blocks in a liquid medium, each of the plurality of building blocks having a plurality of stable radicals, establishing a magnetic field interacting with at least a portion of the plurality of building blocks, guiding with the magnetic field the portion of the plurality of building blocks from a first location in the liquid medium to a second location in the liquid medium, assembling into a first construct the portion of the plurality of building blocks proximate the second location, and treating the first construct with at least one antioxidant to neutralize at least in part the plurality of stable radicals.

System and method for magnetic self-assembly

Growing community of inventors

Storrs, CT, United States of America

Savas Tasoglu