Warner-lambert Company

Mcneil-ppc, Inc.

Other

Sau-Hung Spence Leung

Lori D Kumar

Robert S Leone

Neema Kulkarni

Albert F Sorg

Alain Martin

Pauline H Pan

Michael Rubin

Physiologically acceptable films, including edible films, are disclosed. The films include a water soluble film-forming polymer such as pullulan. Edible films are disclosed that include pullulan and antimicrobially effective amounts of the essential oils thymol, methyl salicylate, eucalyptol and menthol. The edible films are effective at killing the plaque-producing germs that cause dental plaque, gingivitis and bad breath. The film can also contain pharmaceutically active agents. Methods for producing the films are also disclosed.

Fast dissolving orally consumable films

Fast dissolving orally comsumable films

An antimicrobial mouthwash composition that is useful in the prevention and reduction of bad breath, plaque and related gum diseases comprises an antimicrobial effective amount of thymol and one or more other active essential oils; optionally, ethanol in an amount up to about 30% v/v; from about 0.1% to about 8.0% w/v of a peroxide; at least one surfactant in an amount sufficient to solubilize the essential oils; and water. The compositions may be reduced alcohol or alcohol-free compositions. Further a two-part mouthwash system is disclosed, comprising a base composition and a peroxide solution which may be mixed to form an antimicrobial mouthwash composition. The actives not only provide enhanced efficacy but are completely solubilized, thus providing an aesthetically appealing product.

Peroxide/essential oils containing mouthwash compositions and two-part mouthwash systems

The present invention pertains to therapeutic bioadhesive-wound healing compositions useful for treating wounds and increasing the proliferation and resuscitation rate of mammalian cells. The compositions comprise a bioadhesive agent and a therapeutically effective amount of a wound healing composition. In one embodiment the wound healing composition comprises (a) pyruvate; (b) an antioxidant; and (c) a mixture of saturated and unsaturated fatty acids. The therapeutic bioadhesive-wound healing compositions may further comprise medicaments such as antiviral agents, antikeratolytic agents, anti-inflammatory agents, antifungal agents, antibacterial agents, immunostimulating agents, and the like. The bioadhesive-wound healing compositions may be utilized in a wide variety of pharmaceutical products. This invention also relates to methods for preparing and using the bioadhesive-wound healing compositions and the pharmaceutical products in which the compositions may be used.

Bioadhesive-wound healing compositions and methods for preparing and

Growing community of inventors

Parsippany, NJ, United States of America

Sau-Hung Spence Leung