Canon Kabushiki Kaisha

Mitsubishi Chemical Corporation

Satoshi Yuasa

Masahiro Haruta

Hirohide Munakata

Yukuo Nishimura

Yoko Yoshinaga

Yoshinori Tomida

Tatsuki Fukui

Masato Minami

Tetsuya Yano

Kengo Kanazaki

Masaru Ubasawa

Yoko Kuwae

Atsushi Takahashi

Nobuo Nakamura

Toshihiko Miyazaki

Yasuhiko Tabata

Fumio Yamauchi

Yoshiaki Nishimura

Kouichi Sekiya

Katsuo Kawano

Hideaki Takashima

Manabu Ando

Naohiro Kamiya

Jyunji Takashita

Masaaki Shibata

Takashi Iwaki

Masahiko Miyamoto

Naoko Ueda

Mie Morita

Shinjiro Okada

Kenji Saito

Shuzo Kaneko

Shin Kobayashi

Yasuko Tomida

Satoshi Ogawa

Tsuyoshi Furuse

Daisuke Sasaguri

Naoko Miura

Mayuko Kishi

Jun-ichiro Jo

Nobutoshi Mizusawa

Etsuko Sugawa

Etsuro Kishi

Hirokatsu Miyata

Hiroyuki Sugata

Katsuhiko Shinjo

Masanori Sakuranaga

Kouichi Kato

Takashi Hamamoto

Kuniji Osabe

Sachiko Yamauchi

Fumiko Tomatsu

Sachiko Inoue

Shinzaburo Ito

Hiroyuki Aoki

Naoko Inoue

Mika Yamagata

Masahiko Miyamato

Kouhei Nakata

A photoacoustic device comprises a light source configured to generate first and second lights; an irradiation unit configured to generate a first acoustic wave from an object including a contrast agent by irradiating the object with the first light, and then bleach the contrast agent by irradiating the object with the second light and generate a second acoustic wave from the object by irradiating the object with the first light after bleaching; a receiving unit configured to output a first signal upon receiving the first acoustic wave and output a second signal upon receiving the second acoustic wave; and an acquisition unit configured to acquire first information based on the first signal, and acquire second information based on the second signal.

Photoacoustic device

A photoacoustic apparatus comprises a light source; an irradiation unit configured to radiate light from the light source to an object that contains a contrast agent; a receiving unit configured to receive acoustic waves generated when the contrast agent absorbs the light radiated by the irradiation unit and output an electrical signal; a correction processing unit configured to correct a signal strength of the electrical signal, based on a temporal change in a concentration of the contrast agent contained in the object; and an acquiring unit configured to acquire characteristics information on the object, based on the electrical signal that has been corrected by the correction processing unit.

Photoacoustic apparatus

There is provided an ICG-loaded polymer nanoparticle that is dynamically stable, prevents the leakage of contained ICG and the resulting discoloration, and has a high molar absorbance coefficient. The particle contains a hydrophilic dye having a sulfonate group and a hydrophobic polymer, and the particle further contains at least one of a lipid having a positively charged region, a nicotinic acid derivative and a thiamine derivative.

Particle and contrast agent having the particle

The present invention provides a photoacoustic imaging contrast medium which exhibits a high degree of accumulation into a tumor even when some extent of time has passed after performing administration and which facilitates an increase in the intensity of photoacoustic signal produced by the tumor. A compound produced by covalent-bonding of an organic dye which absorbs light in the near-infrared wavelength region and a PEG having a branch.

Compound and photoacoustic imaging contrast medium containing the compound

An iron oxide particle constituting a Resovist (trademark) absorbs a small quantity of light in a near infrared region and emits a weak photoacoustic signal. According to a particle having a catechol-like compound and iron atoms, the particle having a ratio of the number of moles of the catechol-like compound to the number of moles of the iron atoms of 270/10,000 or more, light absorption in the near infrared region increases and a strong photoacoustic signal can be transmitted.

Particle and photoacoustic contrast agent having the particle

Provided is a particle which can stably hold a dye in itself even in an aqueous solution such as serum, in order to solve such a problem of a particle containing ICG, which has been conventionally used in a contrast agent or the like, that the ICG is a dye having a hydrophilic functional group and hence the ICG leaks out of the particle in an aqueous solution such as serum. More specifically, provided is a particle including a hydrophobic dye having a cyanine structure, in which the hydrophobic dye is represented by the following chemical formula (1). 

Particle containing hydrophobic dye having cyanine structure, and contrast agent containing the particle

There is provided a gelatin-ICG complex that can suppress leakage of ICG included therein. The complex has a gelatin derivative including at least one of a phospholipid covalently bonded to a gelatin or a cholesterol covalently bonded to a gelatin, and indocyanine green.

Complex and contrast agent for photoimaging using the same

A method of detecting a contrast agent for photoacoustic imaging provides a high signal intensity. In a contrast agent for photoacoustic imaging, each particle containing an inorganic material supports at least an organic dye having an absorption coefficient in the near infrared region by means of chemical bonding.

Contrast agent for photoacoustic imaging and photoacoustic imaging method

There is provided an organic electroluminescence type two-dimensional color image display panel includes multiple arrayed pixels, the pixels being each formed by arranging organic EL devices having at least red, green, and blue luminescent colors in a certain order, in which each of the organic EL devices has a pair of two parallel sides in a planar shape, the organic EL devices having luminescent colors different from each other are adjacent to each other at the two parallel sides, and the organic EL devices having the same luminescent color are adjacent to each other in a parallel line direction of the two parallel sides, and are arrayed to be of shape of stripes arranged parallel to each other while being slanted with respect to a vertical line.

Color image display panel and method of producing the same, and color image display apparatus

An image display panel of the reflection type includes, in a multilayer structure, a first layer including a periodic planar arrangement of a plurality of electrophoretic elements, each showing one of an opaque black state and a transparent state in response to an input signal, and a second layer including a periodic planar arrangement of a plurality of electrophoretic elements, each showing at least a first color state and a second color state in response to an input signal. An arrangement period of the electrophoretic elements included in the first layer is smaller than an arrangement period of the electrophoretic elements included in the second layer.

Color image display panel and driving method thereof

An electrophoretic display device executes a display on the basis of dispersing charged particles in a liquid and moving the charged particles under application of an electric field. The device includes a first substrate having an electrode, a film mounted on the first substrate and forming a closed portion with a surface of the first substrate, and a liquid positioned in the closed portion, with charged particles being dispersed in the liquid.

Electrophoretic display device and method of producing the same

A method of manufacturing an electron-emitting device that has an electroconductive film containing an electron-emitting region disposed between a pair of device electrodes includes a process of forming the electroconductive film by the steps of (a) applying a metal-containing solution, and (b) heating the solution. The metal-containing solution comprises a compound containing an organic acid group, a transition metal and an alcohol amine, and water.

Method for forming an electron-emitting device using a metal-containing composition

A compound represented by the following general formula (I) which has an antiviral activity:

Phosphonate nucleotide derivatives

A phosphonate nucleotide compound represented by formula (I):

Phosphonate nucleotide compound

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Yokohama, Japan

Satoshi Yuasa