Nippon Oil Fats Co., Ltd.

Sekisui Kagaku Kogyo Kabushiki Kaisha

Sanwa Kagaku Kenkyusho Co., Ltd.

Satoshi Uenoyama

Masayasu Kurono

Makoto Sato

Tsutomu Ishida

Masato Azuma

Takashi Nakagawa

Kazushi Tokita

Katsuhiko Takahashi

A percutaneous-administration-type pharmaceutical preparation of nitroglycerin comprising a backing that is impervious to medicines, and a pressure-sensitive adhesive layer that is disposed on one surface of the backing, wherein the pressure-sensitive adhesive layer contains alkyl (meth)acrylate copolymer in the concentration of 80-95% by weight and the nitroglycerin in the concentration of 5-20% by weight, said copolymer contains as major copolymer components alkyl (meth)acrylate with alkyl groups having 6 or more carbon atoms, which alkyl (meth)acrylates include 2-ethylhexylmethacrylate in the concentration of 40-90% by weight based on the total weight of said alkyl (meth)acrylates, and the copolymer has a rolling ball tack value of 2 or less. The preparation obtained makes it possible for nitroglycerin to be absorbed percutaneously at a controlled rate for long periods of time.

Percutaneous-administration-type pharmaceutical preparation of

Growing community of inventors

both Osaka, Japan

Satoshi Uenoyama