Ricoh Company, Ltd.

Sony Corporation

Chugai Seiyaku Kabushiki Kaisha

Eli Lilly and Company

Satoshi Tsuchiya

Hideo Kanai

Yasunari Mikutsu

Tetsuya Fujioka

Akihisa Mikawa

Masamichi Yamada

Naoyuki Ishikawa

Yukimi Nishi

Jun Mashimo

Teruhiko Kori

Masahiro Nishimoto

Atsushi Matsuo

Hirotaka Kashiwagi

Yoshikazu Nishimura

Masahide Aoki

Satoshi Tanida

Nobuyuki Hori

Kyoko Oguri

Hiroko Ogawa

Shoshin Yoshida

Takuma Kamon

Takahiro Kawai

Tsutomu Sato

Tadashi Ezaki

Hitoshi Yoshino

Yoshiyuki Furuta

Takahiro Hiramatsu

Takuya Shiraishi

Yoshito Saito

Keiji Kanota

Motohisa Ikeda

Yoshio Kubo

Miki Furuya

Hideo Namba

Tomohiro Nakajima

Kazunori Takagi

Naoto Watanabe

Yoshinori Hayashi

Naoki Miyatake

Qiang Yang

Hiroshi Yamazaki

Kensuke Masuda

Mitsuo Suzuki

Yukio Itami

Hajime Watanabe

Magane Aoki

Takehiro Nishimori

Takashi Emura

Tomoya Ohsugi

David Michael Remick

Yasunobu Kuniyoshi

Sakae Okazaki

Radhe Krishan Vaid

Mark Steven Kerr

Kevin Paul Cole

Manabu Wadamoto

Minoru Aoyagi

Xavier A Ortiz-medina

Molly Hess

Adriana Jemison

Derek Robert Starkey

Kenneth Derek Berglund

Ayman D Allian

Audrey Grace Mack

Ashlee Jeanette Davis

Fumiki Kawagishi

Minoru Yamawaki

The present invention provides a compound having the basic structure shown by Formula (I) in which the indole ring and the pyrazolopyridine structure is bound through a substituent, a salt thereof or a solvate of either the compound or a salt of the compound, as well as a preventative agent or a therapeutic agent for non-insulin-dependent diabetes mellitus (Type 2 diabetes) or obesity containing such compound, salt or solvate as an active ingredient.

Pyrazolopyridine derivative having GLP-1 receptor agonist effect

The present invention relates to the synthesis of 3-[(1S,2S)-1-[5-[(4S)-2,2-dimethyloxan-4-yl]-2-[(4S)-2-(4-fluoro-3,5-dimethylphenyl)-3-[3-(4-fluoro-1-methylindazol-5-yl)-2-oxoimidazol-1-yl ]-4-methyl-6,7-dihydro-4H-pyrazolo [4,3-c] pyridine-5-carbonyl] indol-1-yl]-2-methylcyclopropyl]-4H-1,2,4-oxadiazol-5-one, or a salt thereof, and related synthetic intermediate compounds.

Process to make GLP1 RA and intermediates therefor

The present invention provides the compound, 3-[(1S,2S)-1-[5-[(4S)-2,2-Dimethyloxan-4-yl]-2-[(4S)-2-(4-fluoro-3,5-dimethylphenyl)-3-[3-(4-fluoro-1-methylindazol-5-yl)-2-oxoimidazol-1-yl]-4-methyl-6,7-dihydro-4H-pyrazolo[4,3-c]pyridine-5-carbonyl]indol-1-yl]-2-methylcyclopropyl]-4H-1,2,4-oxadiazol-5-one, or a pharmaceutically acceptable salt of the compound, as well as a preventative agent or a therapeutic agent for non-insulin-dependent diabetes mellitus (Type 2 diabetes) or obesity containing such compound.

An image projection apparatus includes a light source, an image generation unit configured to receive light from the light source and generate an image based on the received light, a projection optical system unit configured to project the image generated by the image generation unit, a heat dissipation unit configured to dissipate heat of the image generation unit, and a movable member configured such that a position of the movable member is movable relative to the projection optical system unit, wherein the image generation unit and the heat dissipation unit are mounted on the movable member.

Image formation unit and image projection apparatus

A light source device includes a first light-source unit, a second light-source unit, and a third light-source unit emitting light of spectra different from each other. Each of the first through third light-source units includes a heat dissipator and a light source. The light source includes a light emitting device. The heat dissipators of the first through third light-source units are disposed in an ascending order of values of T/Q of the first through third light-source units, in a direction of cooling air flow. 'Q' represents a heat generation amount from the light source of each of the first through third light-source units, when the light sources are driven to obtain predetermined light intensity and lifespan. 'T' represents a preset, upper-limit temperature for the light emitting device of each of the first through third light-source units to obtain the predetermined light intensity and lifespan.

Light source device, image projector, and method for disposing light source device

A holding structure holds a reflecting mirror. The holding structure includes a reflecting mirror bracket holding the reflecting mirror; a protrusion disposed on the reflecting mirror; a protrusion supporting part disposed on the reflecting mirror bracket and supporting the protrusion; and a spacer disposed between the protrusion supporting part and the reflecting mirror bracket.

Holding structure for holding reflecting mirror, projection optical system unit, optical engine, and image projecting apparatus

An image projection apparatus that generates an image based on image data and projects the image, includes: an image generation element that uses light emitted from a light source to generate an image; a holding unit that rotatably holds the image generation element; and an illumination optical unit that includes one or more optical systems and a light tunnel that is a tubular member surrounding part of a light path from the light source to the image generation element and reflects the light by an inner surface thereof, and that projects the light passing through the light tunnel toward an entire area of a rotatable range of the image generation element.

Image projection apparatus

There is provided a image projection apparatus including an image generation unit for generating an image by using light emitted from a light source, comprising: a movable unit configured to hold the image generation unit and to be able to change a position of the image generation unit; and a drive unit configured to drive the movable unit to move, wherein the movable unit is disposed to move horizontally.

High resolution image projection apparatus with horizontally actuated image generation unit

An image projection device includes: an image generating unit that includes an optical modulation element generating an image using light emitted from a light source; an illumination optical unit that includes one or more optical elements guiding the light emitted from the light source to the image generating unit; a projecting unit that projects the image generated by the image generating unit; a first control unit that performs control to move the image generating unit movable with respect to the illumination optical unit; and a second control unit that performs control to move an illumination area indicating an area illuminated with the light guided to the image generating unit by the illumination optical unit according to a movement amount of the image generating unit.

Image projection device and image projection method to control an illumination area based on movement of image generating unit

A projection lens unit includes a plurality of lenses configured to transmit and emit image light generated by an image generating unit using light from a light source; a barrel configured to hold the plurality of projection lenses; and a heat radiator disposed on the barrel and configured to radiate heat of the barrel to an outside.

Projection lens unit, optical engine, and image projecting apparatus

Growing community of inventors

Kanagawa, Japan

Satoshi Tsuchiya