Dai Nippon Printing Co., Ltd.

Dai Nippon Insatsu Kabushiki Kaisha

Kabushiki Kaisha Toshiba

Shin-etsu Chemical Co., Ltd.

Astellas Pharma Gmbh

Namiki Seimitsu Houseki Kabushiki Kaisha

Satoshi Takeuchi

Masayuki Ando

Hiroki Maeda

Tadafumi Shindo

Tatsuya Tabei

Kenji Asaka

Masanori Akada

Kazuo Watanabe

Hideshi Hattori

Ichiro Tsunoda

Kei Ikegami

Yoichiro Hirao

Takeo Suzuki

Katsumasa Tadokoro

Isamu Harada

Toshimasa Fukagawa

Yoshihiro Nishiue

Akira Misawa

Satoshi Ikeda

Yoshio Inoue

Minoru Takamizawa

Minoru Ueda

Ryohei Takiguchi

Jun Takasaki

Koji Aoyama

Hiroyuki Matsui

Hitoshi Fujii

Yoshiaki Hida

Shigehiko Tahara

Shinji Soga

Isao Baba

Kazunori Hayashi

Satoshi Okazaki

Masahito Sato

Jotarou Suzuki

Chie Okuyama

Takashi Toida

Hideki Takematsu

Yoshiharu Yui

Koutaro Danjo

Etuo Oono

The present application provides a bispecific antibody for preventing or treating an immune inflammatory disease by acting on both human TLR2 and human TLR4 to inhibit human TLR2- and human TLR4-mediated immune inflammatory effects. More specifically, the provided bispecific antibody is a bispecific antibody for human TLR2 and human TLR4, including a heavy chain variable region of an anti-human TLR2 antibody consisting of the amino acid sequence of amino acid numbers 1 to 120 of SEQ ID NO: 4; a light chain variable region of an anti-human TLR2 antibody consisting of the amino acid sequence of amino acid numbers 1 to 113 of SEQ ID NO: 6; a heavy chain variable region of an anti-human TLR4 antibody consisting of the amino acid sequence of amino acid numbers 491 to 609 of SEQ ID NO: 4; and a light chain variable region of an anti-human TLR4 antibody consisting of the amino acid sequence of amino acid numbers 625 to 732 of SEQ ID NO: 4.

Bispecific antibody binding to human TLR2 and human TLR4

To accurately tune the vibration frequency of a suspension during assembly. Secured positionswhere a magnetic circuit partis secured to a suspensionare provided near to each other. From among the secured positions, secured positionssuitable for the characteristics of a suspensionto be mounted and the weight of a magnetic circuit partare selected and secured to each other. Thus, the distance between the securing position and the central position of vibration of a suspensionand a housingcan be changed to tune the frequency to the desired value.

Multifunction-type vibration actuator and mobile terminal device

A liquid crystal optical device including a liquid crystal/polymer composite film including of a matrix polymer composed mainly of a transparent resin having an ionic dissociative group and, dispersed therein, a liquid crystal particle; and conductive substrates sandwiching the liquid crystal/polymer composite film therebetween, at least one of the conductive substrates being transparent. A method for producing the liquid crystal optical device according to the present invention includes the steps of dispersing a liquid crystal in a dispersion medium composed mainly of water to prepare an oil-in-water type emulsion; preparing a composition for electrodeposition through the use of the resultant emulsion and a resin for a matrix polymer; electrodepositing the composition for electrodeposition on a conductive base material to form an electrodeposited coating; and drying the electrodeposited coating to form on the conductive base material a liquid crystal/polymer composite film including a matrix polymer and, dispersed therein, a liquid crystal particle.

Polymer dispersion-type liquid crystal optical device and method for

A liquid crystal optical device including: a liquid crystal/polymer composite film including matrix polymer composed mainly of a transparent resin having an ionic dissociative group and, dispersed therein, a liquid crystal particle; and conductive substrates sandwiching the liquid crystal/polymer composite film therebetween, at least one of the conductive substrates being transparent. A method for producing the liquid crystal optical device according to the present invention includes the steps of dispersing a liquid crystal in a dispersion medium composed mainly of water to prepare an oil-in-water type emulsion; preparing a composition for electrodeposition through the use of the resultant emulsion and a resin for a matrix polymer; electrodepositing the composition for electrodeposition on a conductive base material to form an electrodeposited coating; and drying the electrodeposited coating to form on the conductive base material a liquid crystal/polymer composite film including a matrix polymer and, dispersed therein, a liquid crystal particle.

The present invention provides a process for preparing a printing plate, comprising the steps of: providing an N-type photoconductor layer having an optical memory property on the surface of a substrate having an electrical conductivity at least in its surface to form an N-type photoconductor substrate; subjecting the N-type photoconductor layer to a desired pattern-wise exposure by batch exposure and/or photo-drawing exposure to render exposed areas electrically conductive; immersing the N-type photoconductor substrate in an electrodeposition bath to electrodeposit an ionic organic polymer contained in the electrodeposition bath to form an electrodeposit layer; and washing and drying the electrodeposited substrate to prepare a printing plate. Further, the present invention provides a process for preparing a printing plate, comprising the steps of: subjecting an N-type photoconductor layer provided on an N-type photoconductor substrate to a desired pattern exposure by batch exposure and/or photo-drawing exposure to render exposed areas electrically conductive; electrodepositing an ink-receptive component on the exposed areas; and transferring the ink-receptive component onto a substrate for a printing plate to prepare a printing plate having an ink-receptive area. Furthermore, the present invention provides a process for preparing a printing plate, comprising the steps of: exposing the whole surface or a necessary region of an N-type photoconductor layer provided on an N-type photoconductor substrate, thereby rendering exposed areas electrically conductive; heating the exposed areas by hot pattern drawing to erase the conductivity of the heated areas; and electrodepositing an electrodeposition material on the remaining conductive areas to form an electrodeposit layer.

Printing plate and process for preparing the same

A liquid crystal optical device including a liquid crystal/polymer composite film including a matrix polymer composed mainly of a transparent resin having an ionic dissociative group and, dispersed therein, a liquid crystal particle; and conductive substrates sandwiching the liquid crystal/polymer composite film therebetween, at least one of the conductive substrates being transparent. A method for producing the liquid crystal optical device according to the present invention includes the steps of dispersing a liquid crystal in a dispersion medium composed mainly of water to prepare an oil-in-water type emulsion; preparing a composition for electrodeposition through the use of the resultant emulsion and a resin for a matrix polymer; electrodepositing the composition for electrodeposition on a conductive base material to form an electrodeposited coating; and drying the electrodeposited coating to form on the conductive base material a liquid crystal/polymer composite film including a matrix polymer and, dispersed therein, a liquid crystal particle.

Method of making a polymer dispersed liquid crystal by electrodeposition

Prior to the press-contact between a pattern-transferring flat plate and a transfer-receiving flat plate, at least one of these flat plates is moved to a predetermined position to effect the positioning therebetween, while the positional relation between the pattern-transferring flat plate and the transfer-receiving flat plate is optically observed, and thereafter these flat plates are sequentially press-contacted to each other from an end of the flat plates. Therefore, there is no positional difference between the flat plates which have been correctly positioned, and further the adhesion strength between the transfer pattern and the transfer-receiving flat plate is uniform.

Alignment transfer method

While a pattern side register mark provided on a pattern transferring plate provided with a transfer pattern and a work side register mark provided on a work are optically observed by means of an observation optical system, at least one of the pattern transferring plate and a work surface plate carrying thereon the work is moved in a non-contact state in accordance with information provided by the observation optical system to effect registration between the transfer pattern and the work, so that the pattern transferring plate is pressed to the work thereby to transfer the transfer pattern onto the work.

Alignment method for transfer and alignment device

In a lead frame for use in a plastic mold type semiconductor device having a frame, a die pad on which a semiconductor element is mounted, a tie bar for connecting the die pad to said frame and for supporting the die pad, a plurality of leads whose inner ends of the leads are disposed around the die pad and the leads have inner leads portions which are portions to be sealed in a mold, metal plated region applied only to cover the inner lead and opposite end portions of the the die pad respectively confronting the inner leads, but the tie bar is not plated.

Lead frames for use in plastic mold type semiconductor devices

For printing fine patterns, a fine pattern of a setting type ink is applied to a printing plate surface to become printing elements. Then, the setting type ink thus applied on the printing plate is subjected to a setting treatment thereby to set at least one part of the ink pattern, and thereafter the printing plate and an object to be printed are pressed relatively against each other thereby to transfer the ink pattern onto the print object. The printing plate can be an intaglio plate or a lithographic plate. Fine patterns of printing element widths as fine as 3 .mu.m with an ink film thickness of 2 .mu.m can be printed efficiently with the high precision on various objects including hard and rigid objects.

Method including treatment of ink on a plate to cause hardening at other

A fine pattern is formed by the following steps. A prescribed mask pattern of an electrically insulative material is formed on an electroconductive surface of a base plate of a printing plate, so that the part, other than the mask pattern, of the printing plate becomes an electroconductive printing pattern part. Then, electrolysis is carried out in an electrolyte containing an electrodeposition substance as an ingredient with the printing plate as one electrode and with an opposing electrode, both immersed in the electrolyte, so that the electrodeposition substance is deposited on the electroconductive printing pattern part of the printing plate. Thereafter, the printing plate is withdrawn out from the electrolyte, washed and dried. Then, the deposited substance is transferred onto the surface of a printing object such as a plate of glass or plastic, for forming a pattern thereon. Thereafter, the surface of the printing object is etched with the electrodeposited substance thus transferred as an erosion resistant material. The transfer of the electrodeposition substance without consistency from the printing plate onto the surface of the printing object, followed by etching of the printing object surface, enables an accurate reproduction of a fine pattern on the printing object.

Method of forming fine patterns

A new data recording method is provided in which a consumed amount of predetermined value is recorded in a card memory. Two recording areas are provided in a card memory. The first recording area consists of a plurality of record bits (a through j) which are unchangeable when marked. The second recording area consists of a changeable memory (M). Upper digits of the consumed amount are recorded in the first recording area so as to improve the factor of safety and lower digits of the consumed amount are recorded in the second recording area so as to improve the factor of freedom.

Method of storing a consumed amount in a card memory

A transparent-type hologram comprising a transparent hologram-forming layer and a holographic effect-enhancing layer comprising a thin transparent film, the holographic effect-enhancing layer being laminated on the hologram-forming portion of the transparent hologram-forming layer. The holographic effect-enhancing layer has a refractive index different from that of the transparent hologram-forming layer.

Transparent reflection-type

An image forming material comprises an image forming layer disposed on a support and comprising (a) aqueous composition comprising a hydrophilic binder layer containing metal developing nuclei or their precursor compound, and water and (b) an organic composition comprising an oil-soluble development inhibitor which is a compound having a diazo group or azide group and a water-miscible organic solvent. An image is formed by exposing the image forming layer to patternized light and then contacting it with a developer containing reducible metal ions and a reducing agent thereby to form an image constituted by metal particles grown at the light-exposed parts.

Method and material for image formation

Growing community of inventors

Tokyo, Japan

Satoshi Takeuchi