Asahi Intecc Co., Ltd.

Cellseed, Inc.

Cardio Incorporated

Watanabe, Go

Satoshi Taketani

Yoshiki Sawa

Shigeru Miyagawa

Manabu Shimogami

Shinji Ozawa

Hikaru Matsuda

Go Watanabe

The present invention provides a prosthetic tissue or sheet capable of withstanding implantation operations, which can be used in actual operation and can be produced by culture. The present invention also provides a novel therapy which can substitute for cell therapy. Particularly, the present invention provides a method for producing a prosthetic tissue comprising a cell derived from a part other than myocardium and capable of withstanding implantation operation. The above-described objects of the present invention were partially achieved by finding that by culturing cells under specific culture conditions, the cells are unexpectedly organized into a tissue, and the resultant prosthetic tissue is capable of being detached from culture dishes. The present invention also provides a three-dimensional structure applicable to heart, comprising a cell derived from a part other than the myocardium of an adult.

Three-dimensional tissue structure

It is a purpose to provide a medicinal-liquid injection apparatus in which a needle-like tubular member is smoothly movable in a lumen without damaging an inner circumferential surface of the lumen. It includes that the needle-like tubular member having an acuminate needle portion as a free end portion thereof, in which a medicinal liquid can flow, is inserted in the lumen of a tubular main body insertable in a body of a living being, and a protection member having a flexible portion provided in a state such that the protection member is movable together with the needle-like tubular member and such that the flexible portion is interposed between an inner circumferential surface of the lumen and a tip of the needle portion of the needle-like tubular member.

Medicinal-liquid injection apparatus

Growing community of inventors

Osaka, Japan

Satoshi Taketani