Tanabe Seiyaku Company, Limited

Tanabe Seikaku Co., Ltd.

Satoshi Ohshima

Totaro Yamaguchi

Yoshihisa Yamada

Toyonari Oine

Hiroshi Sugano

Mitsuyoshi Wagatsuma

Toshikazu Miyagishima

Masahiko Seto

Mitsutaka Kawazu

Junichi Tani

Yoshitaka Mushika

Susumu Hatsuno

A cephalosporin compound of the formula: ##STR1## wherein R.sup.1 is hydrogen or lower alkyl;

Cephalosporin compounds

Thiazole intermediates for cephalosporin compounds

A cephalosporin compound of the formula: ##STR1## wherein R.sup.1 is a hydrogen atom, a lower alkyl group, a carboxy(lower)alkyl group, a hydroxy(lower)alkyl group, a carbamoyl(lower)alkyl group, an N-(lower)alkyl-carbamoyl(lower)alkyl group, a cycloalkyl group, a carboxycycloalkyl group, or a tetrazolylmethyl group, R.sup.2 is a hydrogen atom, a lower alkyl group, a formyl group or a lower alkanol group, R.sup.3 is a hydrogen atom, or R.sup.2 and R.sup.3 are combined together to form an aralkylidene group, or a pharmaceutically acceptable salt thereof which is useful as an antimicrobial agent, and process for their preparation.

Cephalosporin compound and process for preparing the same

A 7.beta.-{(Z)-2-(2-aminothiazol-4-yl)-2-[(2-pyrrolidon-3-yl)oxyimino]acetam ido}-3-(1-amino-1H-tetrazol-5-yl)thiomethyl-3-cephem-4-carboxylic acid or a pharmaceutically acceptable salt thereof is useful as an antimicrobial agent.

Pyrrolidomoxine cephalosporins

A quinoline compound of the formula: ##STR1## wherein R.sup.1 is hydrogen or fluorine. A method of preparing the compound (I) is disclosed. The compound (I) and a pharmaceutically acceptable salt thereof are useful as antimicrobial agents.

Quinoline compound useful as antibacterial agents in warm-blooded animals

A compound of the formula: ##STR1## wherein R.sup.1 is hydrogen or hydroxy, R.sup.2 is a group of the formula: --CO-CH(NH.sub.2)-CH.sub.2 COR.sup.3 or --COCH.sub.2 -CH(NH.sub.2)-COR.sup.3, and R.sup.3 is selected from the group consisting of hydroxy, lower alkylamino, di-lower alkylamino, lower alkoxy and hydroxy-lower alkylamino, or R.sup.3 is amino when R.sup.2 is hydroxy. Several methods of preparing the compound [I] are also disclosed. The compound [I] and a pharmaceutically acceptable salt thereof are useful as antimicrobial agents.

Penicillins and processes for preparing the same

Growing community of inventors

Iwatsuki, Japan

Satoshi Ohshima