Jcr Pharmaceuticals Co., Ltd.

Satoshi Nishimuro

Keihide Koh

Yoshikazu Komurasaki

Hiromichi Ishikawa

Tetsuo Yokoyama

Yoshinobu Hanyu

Mariko Okada

Chihiro Shindo

Masato Horie

Hideyuki Kobayashi

Takashi Hirose

Chihiro Shindoh

Mitsuru Hirota

Tomoko Watanabe

A method is disclosed for stabilizing a physiologically active peptide in a process of preparing a powder containing the physiologically active peptide by drying an aqueous liquid containing the physiologically active peptide, wherein the method comprises adding to the aqueous liquid at least one compound selected from the group consisting of a nonionic surfactant, a water-soluble, nonionic, organic binder, hydrogenated lecithin, and mannitol.

Powder containing physiologically active peptide

The present invention provides a process for purifying Tamm-Horsfall glycoprotein (THG) and uromodulin, which permits THG and uromodulin to be purified with enhanced efficiency by the simplified procedure, as well as a method for making the discrimination between both of them.

Process for purifying Tamm-Horsfall glycoprotein or uromodulin their

The present invention provides novel metastasis suppressory agents with a lowered degree of toxicity, comprising ursolic acid or its salt as an active ingredient, which can be administered to patients per os or through injection, thus enabling the patients to receive post-operative ambulatory treatment.

Metastasis suppressory agents

The present invention, using a readily available sulfated chitin as an adsorbent, can permit platelet factor-4 to be recovered through specific adsorption from a solution containing the same factor, in by far increased yields as compared with the conventional process utilizing a heparin-immobilized affinity column, and provides the process for isolating, through purification platelet factor-4 which is suited for a commercial-scale, mass production process, wherein there can be offered the advantages of utilization of more readily available sulfated chitin, simplified procedure and improved production yields for the objective substance.

Process for obtaining platelet factor-4

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Kobe, Japan

Satoshi Nishimuro