Agency of Industrial Science and Technology

Ministry of International Trade & Industry

Satoshi Morimoto

Keishiro Tsuda

Tomowo Kobayashi

Yoshio Tanaka

Shinichi Ohashi

Takashi Hirano

Masaru Shiraki

Shigeru Tsukagoshi

Kazuaki Harata

Shojiro Ito

A detection unit essentially consists of (I) a plurality of calorimetric detection elements for the conduction flow type calorimeter each consisting essentially of a plurality of thermopiles severally supported on heat sinks and (II) a heat insulating member interposed between the adjacent calorimetric detection elements. A calorimetric measuring member for a conduction flow type calorimeter comprises a pair of the detection units and a sample pipe fixed in place between the pair of detection units.

Calorimetric detection unit and calorimetric member for conduction flow

The novel polymeric compound proposed in the invention has a backbone structure formed of a copolymeric moiety of maleic anhydride and divinyl ether and pendant groups thereon derived from an anthracycline-type anti-tumor agent, e.g. adriamycin and daunomycin, or 1-.beta.-D-arabinofuranosylcytosine bonded to the maleic anhydride units in the backbone structure by forming amide linkages, the remaining anhydride units in the backbone structure being hydrolyzed into free acid form or a salt thereof. Both in vitro and in vivo tests indicate that the anti-tumor active pendant groups in the polymeric compound can be released sustainedly to exhibit the anti-tumor activity with greatly decreased side effects unavoidable when the above mentioned anti-tumor agents as such are administrated to a patient in a relatively large dose.

Polymeric compounds with sustained anti-tumor activity and a method for

An inclusion compound-containing composite comprises a container formed of a permeable membrane and an inclusion compound holding therein an active component and enclosed with the container. Through the membrane of the container, the composite releases the active component slowly and continuously over a long time.

Inclusion compound-containing composite

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Ushiku, Japan

Satoshi Morimoto