Riken Corporation

Medical Biological Laboratories Co., Ltd.

Hoya Corporation

Pentax Corporation

University of Washington

Tohoku University

Satoshi Karasawa

Atsushi Miyawaki

Ryoko Ando

Hideaki Mizuno

Hidekazu Tsutsui

Naoki Kikuchi

Rogerio Jun Mizuno

Masanori Maeda

Toshio Araki

Jun Mizuno

Masataka Kinjo

Hiroshi Hama

Takako Kogure

Kenta Saito

Masayoshi Esashi

Hidetomo Tanase

Ryoko Brain Science And Life TechResFound Ando

A confocal optical system comprising a scanning fiber is provided. The scanning fiber is a single-mode fiber of which a first end is shaped as a curved surface. The scanning fiber transmits illumination light to the first end. The illumination light is emitted toward an observation area. The illumination light emanates from the first end. The illumination light emanates from the first end striking a target area within the observation area. The first end receives at least one of reflected light and fluorescence from the target area. The reflected light is the illumination light reflected from the target area. The fluorescence is induced at the target area by illumination from the illumination light.

Confocal optical system

An object of the present invention is to provide a red or orange fluorescent protein, which is characterized in that the difference (stokes shift) between an excitation peak value (wavelength of maximum absorption) and a fluorescence peak value (wavelength of maximum fluorescence) is greatened, so that the maximum fluorescence can be obtained by the maximum excitation. The present invention provides a novel fluorescent protein monomerized by introducing a mutation into a florescent protein derived fromsp., and a novel chromoprotein and fluorescent protein derived from. sp.

Fluorescent protein

An object of the present invention is to provide a novel fluorescent protein derived from. The present invention provides a fluorescent protein derived fromhaving the following properties:

It is an object of the present invention to provide a novel fluorescent protein and a novel chromoprotein. The present invention provides a novel fluorescent protein derived fromsp.,sp. and, and a novel chromoprotein derived from

Fluorescent protein and chromoprotein

The object of the present invention is to provide a novel fluorescent protein in which on and off of fluorescence thereof can be controlled by irradiation with lights of two different wavelengths. The present invention provides a fluorescent protein shown in the following (a) or (b);

It is an object of the present invention to provide a novel chromoprotein and a novel fluorescent protein. The present invention provides chromoproteins derived from, which have certain property, and fluorescent proteins fromand, which have certain fluorescent property.

An optical scanner device, comprising a scanning unit, which casts irradiation light emitted from a light source in an arbitrary direction to scan an observation object, an objective lens system, which converges the irradiation light on the observation object, and a photo-detector unit, which is disposed on an optical axis of the objective lens system to have the irradiation light transmit therethrough, is provided. A position of the irradiation light converged on the observation object is detected based on a position of a light spot of the irradiation light transmitting through the photo-detector unit.

Optical scanner device

An object of the present invention is to provide a novel fluorescent protein derived from organisms other than. According to the present invention, there is provided a fluorescent protein derived fromsp., which has the following properties:

[object Object]

An object of the present invention is to provide a chromoprotein derived from. The present invention provides a chromoprotein derived fromhaving the following properties: (1) the absorption maximum wavelength is 610 nm, and fluorescence is not emitted; (2) the molar absorption coefficient is 66,700 at 610 nm; and (3) the pH sensitivity of light-absorbing property is stable at between pH 4 and pH 10.

Growing community of inventors

Tokyo, Japan

Satoshi Karasawa