Hoya Corporation

Honda Motor Co., Ltd.

Saitama Medical University

Rnai Co., Ltd.

Keihin Corporation

Satoshi Inoue

Shuichi Takeuchi

Kazuhiro Ikeda

Tomoyoshi Koyama

Suguru Takishima

Tomohiko Hatakeda

Koji Hakoda

Naoto Hashimoto

Yuta Yoshida

Kazunori Fukuma

Naoki Yamagata

Tetsuya Fukuda

Kuniko Inoue

Daisuke Koreeda

Koichi Takaku

Takahiro Sasaki

Nobutaka Nakajima

Kazuya Mizumoto

Takahide Kato

Hirotaka Otaki

Ikeda Kazuhiro

A double-stranded nucleic acid molecule for suppressing expression of non-coding RNA, the double-stranded nucleic acid molecule including: (a) a sense strand containing a nucleotide sequence corresponding to a target sequence set forth in any one of SEQ ID NOs: 26 to 31; and (b) an antisense strand containing a nucleotide sequence which is complementary to the sense strand in the (a) to form a double strand with the sense strand, wherein the non-coding RNA contains a base sequence set forth in any one of SEQ ID NOs: 2 to 4, a part of the base sequence, or both of the base sequence and the part.

Double-stranded nucleic acid molecule, DNA, vector, cancer cell growth inhibitor, cancer cell migration inhibitor, and drug

A double-stranded nucleic acid molecule for suppressing expression of non-coding RNA, the double-stranded nucleic acid molecule including: (a) a sense strand containing a nucleotide sequence corresponding to a target sequence set forth in any one of SEQ ID NOs: 5 to 11 and 26 to 31; and (b) an antisense strand containing a nucleotide sequence which is complementary to the sense strand in the (a) to form a double strand with the sense strand, wherein the non-coding RNA contains a base sequence set forth in any one of SEQ ID NOs: 1 to 4, a part of the base sequence, or both of the base sequence and the part.

In a fuel gas circulation apparatus, a diffuser is accommodated in an attachment hole of a body. An injector is provided upstream of the diffuser through an attachment. A vibration absorption member made of elastic material is provided between a proximal end of a large diameter portion of this diffuser and a distal end of a main body in the attachment, and a ring member is provided adjacent to the vibration absorption member.

Fuel gas circulation apparatus

A solenoid valve includes a body having a flow channel, and a solenoid part coupled to the body. The solenoid part includes a core housing. A movable core can be accommodated inside the core housing. A flange part of the core housing is expanded radially outwardly from a guide part which guides the movable core. Further, a thick portion is provided at a boundary portion between the flange part and the guide part on a core part side. The thick portion becomes gradually thick toward the guide part.

Solenoid valve

A hydrogen injection apparatus has an injector attached to an attachment hole of a body. The injector can inject hydrogen. A mounting member made of metal is provided on the outer circumferential side of the injector. An annular elastic member is provided in contact with a base of the mounting member. At the time of mounting the injector to the attachment hole, an elastic member and the mounting member are assembled in a manner that the elastic member and the mounting member are accommodated in a support base of an attachment provided at an opening of the attachment hole.

Hydrogen injection apparatus

In a valve apparatus, an annular contact portion made of elastic material is provided on a valve portion of a valve plug. A plurality of annular grooves are formed on a proximal end surface of a valve seat member which abuts against the contact portion. The annular grooves are formed around a communication hole through which fluid flows. The annular grooves have different diameters, and are concentric with one another.

Valve apparatus

A valve device is equipped with a body, a valve element drive mechanism, and a housing. The body has a tubular insertion section, in which a movable member of the valve element drive mechanism is inserted. A first flange is formed at an end of the insertion section that faces the housing. Furthermore, a ring is fitted externally on an outer side wall of the first flange. By projections, which are provided on an inner side wall of the ring, being embedded in an outer side wall of the insertion section, the ring is made integral with the first flange. The housing is of a bottomed tubular shape that covers the valve element drive mechanism, and an edge of an open end of the housing is crimped to the first flange through the ring.

Valve device

An object of the present invention is to provide a fuel cell system and a method of operating the fuel cell system which is difficult to give an uncomfortable feeling to a driver or passenger by operation sound of the injector while satisfactorily discharging water. The fuel cell system includes a fuel cell stack having an anode flow path, an injector for supplying hydrogen at a predetermined drive cycle toward the anode flow path by being opened, and an ECU for controlling the injector, wherein the ECU performs a valve opening time extension step in which hydrogen is supplied in a valve opening time longer than that in next and previous drive cycles.

Fuel cell system and method of operating fuel cell system

A double-stranded nucleic acid molecule including (a) a sense strand which includes a nucleotide sequence corresponding to a target sequence indicated by any one of SEQ ID Nos.: 1 to 21, and (b) an antisense strand which includes a nucleotide sequence complementary to that of the sense strand specified in (a), wherein the double-stranded nucleic acid molecule is for suppressing the expression of at least one of APP and EBAG9 genes.

Double-stranded nucleic acid molecule, cancer cell proliferation inhibitor and pharmaceutical agent suitable for prevention or treatment of cancer

A method for adjusting a tilt angle of an objective lens with respect to one of a multilayer optical disc having a plurality of recording layers and an optical axis of an optical information recording/reproducing apparatus, wherein a use wavelength &#x3bb; and a numerical aperture NA are defined by conditions: 390&#x3c;&#x3bb;&#x3c;420 and 0.75&#x3c;NA&#x3c;0.90. The method includes determining the tilt angle of the objective lens such that a spot quality defined through a predetermined transparent parallel flat plate matches a predetermined standard, and tilting the objective lens to have the determined tilt angle. When t1 represents a thickness of the predetermined transparent parallel flat plate and t2 represents a design protective layer thickness at which a coma caused when off-axis light is incident on the objective lens becomes smallest, t1 and t2 satisfy: &#x2212;0.015&#x3c;t1&#x2212;t2&#x3c;0.005.

Tilt angle adjustment method for objective lens and optical information recording/reproducing apparatus

An optical information recording/reproducing optical system where resin material has Tg&#x3e;115&#xb0; C., first, second and third films are on an optical disc side of an objective lens and surfaces of an optical element, respectively, a light source side of the objective lens has a fourth film having four or more layers not containing Ti, each of the first, second and third films includes a non-high refractive index layer made of one of silicon oxide, aluminum oxide, aluminum fluoride and magnesium fluoride or a mixture of at least two of them, each of the first, second and third films is not made of one of Ti, Ta, Hf, Zr, Nb, Mo and Cr, a layer of the fourth film closest to a base material is the non-high refractive index layer. The fourth film satisfies 350&#x3c;&#x3bb;&#x3c;420 and 600&#x3c;&#x3bb;&#x3c;750, and reflectivity thereof decreases monotonously.

Optical information recording/reproducing optical system and optical information recording/reproducing apparatus

An objective optical system for an optical information recording/reproducing apparatus, at least one surface of the objective optical system being configured to be a phase shift surface having a phase shift structure, wherein: the phase shift surface has a first area contributing to converging first, second and third light beams onto recording surfaces of first, second and third optical discs, respectively; in the first area, the phase shift surface has at least two types of phase shift structures including a first phase shift structure having first steps and a second phase shift structure having second steps; the phase shift surface has a plurality of combinations of annular zones which satisfy a condition:0.95&#x3c;1/2&#x3c;1.05&#x2003;&#x2003;(1), andthe phase shift surface satisfies a following condition:&#x2212;3.00&#x3c;&#x394;&#x3c6;1/&#x394;&#x3c6;2&#x3c;&#x2212;0.10&#x2003;&#x2003;(2).

Optical information recording/reproducing apparatus and objective optical system for the same

An optical information recording/reproducing apparatus for an optical disc using a light beam having a wavelength of &#x3bb; including: an objective lens that converges the light beam onto a recording surface of the optical disc and satisfies a condition: 

Objective lens and optical information recording/reproducing apparatus

An optical information recording/reproducing optical system, comprising a light source; an optical element converting a laser beam into a substantially collimated beam; and an objective lens, wherein a wavelength &#x3bb; (unit: nm) of the laser beam falls within a range of 400&#x3c;&#x3bb;&#x3c;410, the optical element and the objective lens are made of same resin materials or different resin materials having a glass transition temperature of Tg&#x3e;115&#xb0; C., each of optical surfaces is configured not to have an optical thin film which contains at least one of or elements of titanium, tantalum, hafnium, zirconium, niobium, molybdenum and chromium, each of optical surfaces of the optical element is provided with an antireflection film made of one of or a mixture of at least two of silicon oxide, aluminum oxide, aluminum fluoride and magnesium fluoride, and a following condition is satisfied 

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Saitama, Japan

Satoshi Inoue