Shimadzu Corporation

Satoru Watanabe

Takeshi Yoshida

Takayuki Iriki

Tomohiro Shagawa

Taichi Tomono

Fuyuki Okamoto

Chihiro Yasui

Takashi Inoue

Yuma Okabe

An analysis assistance device includes a chromatogram generator that generates a chromatogram using measurement data obtained from an analysis device, an area calculator that calculates an area percentage of each peak included in the chromatogram, a determiner that determines a separation state of each peak included in the chromatogram, and an analysis assistance information outputter that outputs analysis assistance information to a display. The analysis assistance information outputter includes a chromatogram outputter that outputs the chromatogram generated by the chromatogram generator to the display and also outputs information to display one peak in an identified manner when the one peak has an area percentage of not less than a predetermined threshold value, and the determiner determines that the one peak is an unseparated peak.

Analysis assistance device, method, and program for an analysis used in liquid chromatography

An analysis assistance device includes an estimator that estimates distribution of measurement quality index data using a plurality of analysis condition data to be provided to an analysis device and a plurality of measurement data obtained in the analysis device based on the plurality of analysis condition data, and a measurement quality index outputter that outputs for display a region where the measurement quality index data is not less than a predetermined threshold value as a design space, and the measurement quality index outputter outputs the region of the design space in an enlarged manner by cutting off at least part of a region other than the design space in a distribution region of the measurement quality index data.

Analysis assistance device, method, and program for searching for an analysis condition for use with a liquid chromatography system

Analysis control software is installed in an analysis control device. The analysis control software is the software for controlling an analysis device, and has a function of causing a display to display one or a plurality of operation images for receiving an operation for inspecting the analysis control software. In a validation device, operation commands for performing an operation on one or a plurality of operation images are sequentially generated by an inspection executor with the one or plurality of operation images displayed in the display, whereby an inspection is executed by the analysis control software.

Validation device, validation method and non-transitory computer readable medium

A sample measurement device () includes a measurement unit () configured to measure a sample containing a plurality of components according to a measurement condition () including a plurality of parameters (), and a data processing unit () configured to acquire measurement data, and the data processing unit is configured to acquire a distribution () of a measurement quality indicator () according to the measurement condition based on the measurement data (), and identify a peak () of each of the components in the measurement data based on the distribution of the measurement quality indicator and the parameters used when the sample is measured.

Sample measurement device and measurement sample identification method

The automatic suitability determination system includes a check document storing part, a check document retrieving part, a determination test execution part, and a suitability determination part. The check document storing part stores suitability check documents. The check document retrieving part is configured to read out the suitability check document related to a determining target component of operational suitability from the check document storing part. The determination test execution part is configured to read information contained in the suitability check document read out by the check document retrieving part and to execute tests of suitability determination items specified in the suitability check document by making the determining target component of the operational suitability operate based on the information. The suitability determination part is configured to determine, based on results of the tests executed by the determination test execution part, suitability for the suitability determination items corresponding to the tests.

Automatic suitability determination system

In a chromatograph, a mobile phase is supplied to any of a plurality of columns by a mobile phase supplier, and a sample is supplied to the column by a sample supplier. The sample that has passed through the column is detected by a detector. In a chromatographic control device, a flow rate of the mobile phase for the analysis with use of the column is registered by a flow rate registrar in association with column specifying information for specifying each column. The flow rate of the mobile phase registered in association with a selected column is acquired from registered content of the flow rate registrar. The chromatograph is controlled such that the analysis is performed by an analysis controller while the mobile phase is supplied to the selected column with use of the selected column and the flow rate of the mobile phase acquired by a flow rate acquirer.

Chromatographic control device, chromatographic system, chromatographic control method, chromatographic control program and non-transitory computer readable medium

An autosampler includes a retention path for injecting a sample into a mobile phase that flows through an analysis path to a column, the retention path including a needle at a downstream end and holding the sample, an injection path including a port at an upstream end for injecting into the analysis path, the sample injected from the needle into the port, a low-pressure path having an upstream end connected to a pump, and a valve that can switch between a first state in which an upstream analysis path and a downstream analysis path are connected and a downstream end of the low-pressure path and an upstream end of the retention path are connected and a second state in which the upstream analysis path and the upstream end of the retention path are connected and the downstream end of the injection path and the downstream analysis path are connected.

Chromatograph and sample injection apparatus

An analysis assistance device includes an estimator that estimates distribution of measurement quality index data using a plurality of analysis condition data to be provided to an analysis device and a plurality of measurement data obtained in the analysis device based on the plurality of analysis condition data, a calculator that calculates the measurement quality index data from the measurement data obtained from the analysis device, and a comparison outputter that compares and outputs for display the measurement quality index data estimated by the estimator and the measurement quality index data calculated by the calculator.

Analysis assistance device, analysis assistance method and non-transitory computer readable medium storing analysis assistance program

An online HPLC dissolution test system includes a dissolution tester and a liquid chromatograph. An autosampler of the liquid chromatograph includes at least one flow vial, a sampling needle and an injection port. the flow vial is connected to the dissolution tester via a pipe and is for storing a sample solution supplied from the dissolution tester therein. The sampling needle is for collecting the sample solution by sucking from the flow vial. The injection port is for injecting the sample solution from the sampling needle into the analysis channel. The controller of the liquid chromatograph includes an immediate analyzing execution part configured to cause the autosampler to execute immediate analyzing operation for sucking the sample solution in the flow vial with the sampling needle and directly injecting the sample solution into the injection port when the sample solution is supplied from the dissolution tester to the flow vial.

Liquid chromatograph and dissolution test system

An organic solvent containing liquid that does not include a component to be detected by a detector is used as a first solvent, and an organic solvent containing liquid that includes the component to be detected and is adjusted to have a concentration of an organic solvent that prevents a separation column from actually holding the component to be detected is used a second solvent. Further, a mobile phase is sent while a setting value of a concentration of the second solvent in the mobile phase is changed over time with the separation column provided on an analysis flow path, and an actual concentration of the second solvent in the mobile phase is found based on a detection signal of the detector when the mobile phase is sent at each setting value.

Method of measuring accuracy of concentration in sending liquid in gradient and liquid chromatograph having function of executing method

An online HPLC dissolution test system includes a dissolution tester and a liquid chromatograph. An autosampler of the liquid chromatograph includes at least one flow vial, a sampling needle and an injection port. The flow vial is connected to the dissolution tester via a pipe and is for storing a sample solution supplied from the dissolution tester therein. The sampling needle is for collecting the sample solution by sucking from the flow vial. The injection port is for injecting the sample solution from the sampling needle into the analysis channel. The controller of the liquid chromatograph includes an immediate analyzing execution part configured to cause the autosampler to execute immediate analyzing operation for sucking the sample solution in the flow vial with the sampling needle and directly injecting the sample solution into the injection port when the sample solution is supplied from the dissolution tester to the flow vial.

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Kyoto, Japan

Satoru Watanabe