Amano Pharmaceutical Co., Ltd.

Nippon Oil Fats Co., Ltd.

Satoru Suzuki

Shotaro Yamaguchi

Kuniyoshi Matsunaga

Kimiyasu Isobe

Yuji Nakanishi

Yoshinao Koide

Teruo Kanazawa

Tsukasa Motohira

Tetsunori Akiba

Kenichi Takeuchi

Toshinori Ima

This invention provides an L-&agr;-glycerophosphate oxidase (GPO) having excellent properties such as stability, heat resistance and reactivity. A recombinant GPO obtained by replacing an amino acid of a specified position of an amino acid sequence deduced from the,No. 7044 GPO gene or DNA coding for the GPO with other amino acid has excellent thermal stability and reactivity. That is, the invention provides modified forms of the GPO having the amino acid sequence of Sequence No. 1 in the Sequence Listing, in which the 130-position leucine counting from the N-terminus of the GPO is replaced by other amino acid and/or the 225-position serine counting from the N-terminus of the GPO is replaced by other amino acid and/or the 298-position threonine counting from the N-terminus of the GPO is replaced by other amino acid and/or the 420-position aspartic acid counting from the N-terminus of the GPO is replaced by other amino acid.

L-&agr;-glycerophosphate oxidase gene, recombinant DNA, and method for producing modified L-&agr;-glycerophosphate oxidase gene

A housing for a gas generating composition comprises an igniter chamber for retaining an igniter material. A combustion chamber is formed around the igniter chamber, and a gas generating composition is disposed in the combustion chamber. A cooling chamber with a gas exhaust port is formed around the combustion chamber. A coolant for cooling gas is accommodated in the cooling chamber. The igniter chamber, the combustion chamber and the cooling chamber communicate with one another through ports. A first shell constitutes the top wall of the combustion chamber, an intermediate wall between the combustion chamber and the cooling chamber, and at least the bottom wall of the cooling chamber. The first shell is integrally formed of a metal plate with an even thickness, and opens downward at its center portion and is open at least upward at its outer surface. An igniter housing constitutes at least the peripheral wall of the igniter chamber. The igniter housing is joined to the inner surface of the top wall of the first shell, and is open downward. A second shell is open downward, and is joined to the first shell at the periphery of the opening. The second shell and the first shell cooperate to define the cooling chamber. A cover is joined to the first shell and the igniter housing to constitute the bottom walls of the igniter chamber and the combustion chamber.

Housing for gas generating composition

Lipase isolated from Penicillium characterized by the following properties:

Lipase, its production and use for assay of triglycerides

Growing community of inventors

Aichi, Japan

Satoru Suzuki