Fujisawa Pharmaceutical Company, Ltd.

Satoru Kuroda

Masayoshi Murata

Hiroaki Ohtake

Toshiyuki Chiba

Hideo Tsutsumi

Kohji Hattori

Fumiyuki Shirai

Mitsuru Ohkubo

Hideko Nakamura

Hisashi Takasugi

Hiroshi Kayakiri

Toshiaki Aoki

Atsushi Akahane

Kiyoshi Taniguchi

Naoaki Fujii

Yosuke Fujii

Hitoshi Hamashima

Minoru Sakurai

Hiromichi Itani

Yasuyo Tomishima

Jiro Seki

Shunsuke Goto

Kenichi Washizuka

Masashi Imanishi

Masatoshi Minagawa

Keiichi Koga

Ryoki Orii

Yutaka Nakajima

Kayoko Harada

Eiki Oikawa

Yasuyo Shimizu

The present invention relates to a compound formula (I) wherein X is bond or &mdash;O&mdash;CH &mdash;, (II) or (III) R is hydrogen or an amino protective group, a is phenyl, indolyl or carbazolyl, each of which may be substituted with one or two substituent(s), and B is hydrogen; halogen; lower alkyl; lower alkoxycarbonyl; cyclo(lower)alkyl; or a heterocyclic group, naphthyl, 1,2,3,4-tetrahydronaphthyl, benzyl or phenyl, each of which may be substituted with one or two substituent(s), or a salt thereof. The compound (I) of the present invention and pharmaceutically acceptable salts thereof are useful for the prophylactic and/or the therapeutic treatment of pollakiures or urinary incontinence.

Aminoalcohol derivatives

A beta-alanine derivative of the formula (I) wherein R is hydrogen atom or an amino protective group; A is a lower alkylene group or a lower alkenylene group; R is hydrogen atom or an amino group which may be substituted with an acyl group; R is hydrogen atom or an aryl or aralkyl group which may be substituted with one or more of hydroxy and/or lower alkoxy, a moiety represented by the formula (II), which is a bivalent N-containing 6- to 8-membered heterocyclic group, or a pharmaceutically acceptable salt thereof.

Beta-alanine derivatives and their use as receptor anatgonists

N-&lsqb;(R)-1-&lsqb;3-(4-piperidyl)propionyl&rsqb;-3-piperidylcarbonyl&rsqb;-2(S)-acetylamino-&bgr;-alanine trihydrate, compositions thereof, and methods for its use

Pyrazolopyridine compound and pharmaceutical use thereof

1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid compounds

1-Azabicyclo[3.2.0]hept-2-ene-2-carboxyic acids having antimicrobial activity have been prepared.

Growing community of inventors

Osaka, Japan

Satoru Kuroda