National Institute of Advanced Industrial Science and Technology

National Institute of Technology and Evaluation

Kyushu University

National Research Institute of Brewing

Kurume Research Park Co., Ltd.

Japan Software Management Co., Ltd.

Satoru Kuhara

Kiyoshi Asai

Masayuki Machida

Keietsu Abe

Naotake Ogasawara

Katsuya Gomi

Motoaki Sano

Hideki Nagasaki

Osamu Akita

Taishin Kin

Akira Hosoyama

Shotaro Yamaguchi

Hisanori Nasu

Yasuji Koyama

Yoshizumi Ishino

Yuji Oki

Katsuhiko Kitamoto

Kotaro Ito

Kenichiro Matsushima

Toshiharu Ninomiya

Manabu Arioka

Jun Hata

Kazuhiro Fujita

Yoshinori Katakura

Tasuku Nakajima

Misao Sunagawa

Tetsuji Masaoka

Takanori Kobayashi

Ichiro Nakayama

Akito Mugita

Hiroaki Ono

A disease risk assessment apparatus () includes an assessment unit () for assessing the risk of developing dementia in a subject, based on the concentration of an amino acid in the blood of the subject. The amino acid includes at least one selected from the group consisting of histidine, phenylalanine, leucine, isoleucine, methionine, threonine, glycine, glutamine, lysine, asparagine, homocysteine, cystathionine, S-adenosylmethionine, and S-adenosylhomocysteine.

Disease risk assessment apparatus, disease risk assessment method, computer readable medium, and food for dementia prevention

The present invention provides an inspection chip using light, which is able to provide an irradiation of light at a high precision. The present invention further provides an inspection chip capable of carrying out the inspection of a sample in a simple manner by using a plurality of lights. The inspection chip of the present invention comprises a light amplifier element and a sample holding section for holding a sample, in which the light amplifier element is oriented so as to face to the sample holding section, so that the light emitted from the light amplifier element can irradiate the sample held in the sample holding section.

Inspection chip equipped with a light amplifier element

It is intended to provide koji mold-origin phospholipase Aand a DNA encoding it. Namely, phospholipase Acomprising the following protein (a) or (b): (a) a protein having an amino acid sequence represented by SEQ ID NO: 1 or 2; and (b) a protein having an amino acid sequence derived from an amino acid sequence represented by SEQ ID NO: 1 or 2 by a partial modification and serving as phospholipase A.

[object Object]

There is provided a method for the detection of a base sequence of interest when amount of a sample DNA or RNA is little and plural base sequences of interest to be detected are present in the sample DNA or RNA. The Problem is solved by a method for the detection of an base sequence of interest in a sample DNA or RNA comprising the steps of (1) contacting a sample DNA or RNA to a probe DNAs or RNAs in an aqueous solution to form a hybridization complex; (2) isolating the hybridization complex; (3) dissociating the complex to recover the probe DNAs or RNAs; and (4) identifying the said probe DNAs or RNAs to detect an base sequence of interest in the sample DNA or RNA.

Method for detection of base sequence of interest

The purpose of the present invention is to isolate a gene encoding novel exo-, or endo-&#x3b2;--glucanase, to obtain a microorganism having an enhanced expression of said gene and to degrade &#x3b2;--glucan to its low molecular weight form by means of said enzymes. The present invention relates to a gene or DNA encoding novel enzymes having &#x3b2;--glucanase activity (exo-, or endo-&#x3b2;--glucanase), a recombinant expression vector comprising them, a microorganism having the recombinant expression vector, the novel enzymes having &#x3b2;--glucanase activity, and a method for the production of said enzymes.

Genes of cell wall-degrading enzymes derived from aspergillus, and method for the production the enzymes

A completely novel glutaminase is provided: (a) a protein consisting of an amino acid sequence represented by SEQ ID NO: 2, or (b) a protein consisting of an amino acid sequence derived from the amino acid sequence represented by SEQ ID NO: 2 by deletion, substitution or addition of one or more amino acids, and possessing glutaminase activity. This protein is a novel glutaminase possessing excellent thermostability and the like.

Thermostable glutaminase and thermostable glutaminase gene

Growing community of inventors

Fukuoka, Japan

Satoru Kuhara