Smc Corporation

Taiho Pharmaceutical Company Limited

Banyu Pharmaceutical Co. Ltd

Furukawa Co., Ltd.

Merck Sharp + Dohme Corp.

Msd K.k.

Nikon-essilor Co., Ltd.

Satoru Ito

Hisashi Yajima

Masayuki Ishikawa

Gen Tsuchiya

Takeshi Sagara

Takehiko Kanazawa

Toshifumi Kimura

Hiroshi Kawamoto

Hisashi Ohta

Takahiro Ochi

Junqing Guo

Sachie Otsuki

Atsushi Satoh

Akio Sato

Gentaroh Suzuki

Junji Sakashita

Yukari Hirata

Yasushi Nagatomi

Kaname Inoue

Huiyuan Geng

Nobuhiro Fujiwara

Solomon D Kattar

Jason David Katz

Joon Jung

James Patrick Jewell

Seiji Takanashi

Katsumasa Nonoshita

Rachel Nicola MacCoss

Hiroshi Sootome

Koichiro Kanda

Masaaki Kikuchi

Shogo Suzuki

Masaoki Tomoda

Yongquan Hou

Hirotatsu Okumura

Kei Ishimura

Shunichi Ochi

A first flow path area at a position where one of multiple openings of a sleeve and one of multiple grooves of a spool overlap with each other is different in size from a second flow path area at a position where another one of the openings of the sleeve and another one of the grooves of the spool overlap with each other. The one opening and the one groove form a flow path for connecting one of one pressure chamber and the other pressure chamber to a fluid supply source, due to displacement of the spool. The other opening and the other groove form a flow path for connecting another one of the other pressure chamber and the one pressure chamber to a fluid discharge port, due to the displacement of the spool.

Servo valve

A drive device for driving a fluid pressure cylinder has an air supply source which supplies air, a switching valve which switches between the supply and discharge of the air to and from the fluid pressure cylinder, bypass piping which connects the head-side cylinder chamber and rod-side cylinder chamber of the fluid pressure cylinder, and a bypass switching valve which switches between the states of flow of air through the bypass piping. Air in the head-side cylinder chamber is supplied to the rod-side cylinder chamber through the bypass piping by setting the bypass switching valve to an open state in a return stroke of the fluid pressure cylinder.

Drive method and drive device for fluid pressure cylinder

A servo valve has a movable element disposed inside a body, and a drive unit to slide the movable element in the axial direction. A first elastic portion on one end portion side of the body has a first elastic force to press the movable element toward the drive unit connected to another end portion of the body; a second elastic portion on another end portion side of the body has a second elastic force to press the movable element toward the one end portion side of the body. A connecting portion is connected to the second elastic portion, wherein at a neutral position of the movable element, the connecting portion abuts against an inner peripheral surface of the body and against the movable element. An end of one of the first and second elastic portions is fixed directly to the movable element, and an end of the other of the first and second elastic portions is connected to the connecting portion.

A servo valve is provided with a first elastic portion, a second elastic portion, and a connecting portion. The first elastic portion extends in an X direction inside a valve body and has a first elastic force exerted on a movable element toward an X2 direction. The second elastic portion extends in the X direction inside the valve body and has a second elastic force exerted on the movable element toward an X1 direction. The connecting portion is connected to the first elastic portion and the second elastic portion inside the valve body, and is in abutment against a step portion of the valve body and a spool of the movable element at a neutral position of the movable element.

A thermoelectric conversion material having excellent thermoelectric performance over a wide temperature range, and a thermoelectric conversion module providing excellent junctions between thermoelectric conversion materials and electrodes. An R-T-M-X-N thermoelectric conversion material has a structure expressed by the following formula: RTMXN(0&#x2264;r&#x2264;1, 3&#x2264;t&#x2212;m&#x2264;5, 0&#x2264;m&#x2264;0.5, 10&#x2264;x&#x2264;15, 0&#x2264;n&#x2264;2), where R represents three or more elements selected from the group consisting of rare earth elements, alkali metal elements, alkaline-earth metal elements, group 4 elements, and group 13 elements, T represents at least one element selected from Fe and Co, M represents at least one element selected from the group consisting of Ru, Os, Rh, Ir, Ni, Pd, Pt, Cu, Ag, and Au, X represents at least one element selected from the group consisting of P, As, Sb, and Bi, and N represents at least one element selected from Se and Te.

Thermoelectric conversion material and thermoelectric conversion module

An optical component includes: a plastic base which has a convex surface and a concave surface; and a multilayer film which is disposed on at least the convex surface of the plastic base. The multilayer film has an average reflectivity of 2% to 10% over a wavelength range of 400 nm to 500 nm.

Optical component and method of manufacturing the same

A thermal stress of electrode members (to) due to an operation temperature may be relaxed by thermal stress relaxation layers (to), and thus peeling of the electrode members (to) due to thermal stress at the operation temperature may be prevented in a satisfactory manner. Furthermore, diffusion of a constituent component of the thermoelectric conversion members (and) due to the operation temperature and the like may be prevented by diffusion prevention layers (to), and thus durability and stability of the thermoelectric conversion module () may be improved.

Thermoelectric conversion module

The present invention provides a compound represented by Formula (I) (wherein R, X, X, Y, and Z are as defined in the specification), or a salt thereof.

3,5-disubstituted alkynylbenzene compound and salt thereof

The present invention provides a new compound that has an inhibitory action against EGFR and that has cell growth inhibitory effects. The present invention further provides a pharmaceutical preparation useful for preventing and/or treating cancer, based on the EGFR inhibitory effect of the compound. A compound represented by the following Formula (I) or a salt thereof.

Quinolyl pyrrolo pyrimidyl condensed-ring compound and salt thereof

The present invention relates to pyrazolopyridines and imidazopyridines which are inhibitors of the kinase PDK1 and are thus useful for the treatment of myeloproliferative disorders or cancer. The compounds are also useful as inhibitors of other kinases such as FGFR3, NTRK3, RP-S6K and WEE1. Furthermore, the present compounds also selectively inhibit microtubule affinity regulating kinase (MARK) and are therefore useful for the treatment or prevention of Alzheimer's disease.

Therapeutic compounds

The present invention provides the compounds represented by formula (I): (I) or pharmaceutical salts thereof, wherein: 

Diaryl-substituted five-membered heterocycle derivative

The present invention relates to a compound represented by the formula (I): or a pharmaceutically acceptable salt thereof, wherein: Ris a linear or branched alkoxy group, a cycloalkoxy group, a linear or branched lower alkyl group, etc.; Ris halogen atom, a lower alkyl group, etc.; Qis carbon atom or nitrogen atom; Qis carbon atom which may be substituted with oxo group; the formula (III):&#x2003;&#x2003;(II)is a single bond or a double bond; A is a group selected from the group consisting of the substitutent group &#x3b1;; and Ris hydrogen atom, a lower alkyl group, cyano group, an alkoxy group or a trialkylsilyl group; having an mGluR1 inhibiting action and being useful as treatment and/or prevention of convulsion, acute pain, cerebral disturbance such as cerebral infarction or transient cerebral ischemia onset, anxiety, chemical dependency or Parkinson's disease.

Biaryl derivatives

A magnetic damper comprises a movable braking plate for receiving an operating element of an actuator, and a stator for attracting the braking plate by a magnetic force. A magnetic attraction force acting between the stator and the braking plate is used as a braking force for stopping the operating element.

Magnetic damper and actuator having the same

A plurality of jaw members for gripping a work piece on a casing , to be opened or closed freely, a driving part having a driving rod to be moved linearly, reciprocally, a converting mechanism for converting the linear reciprocal motion of the driving rod into the opening or closing operation of the jaw members , a position detecting part capable of detecting the operating position of the jaw members for all the stroke, comprising a scale displaced synchronous with the driving rod , and a reader for reading the calibration engraved on the scale , and a linear guide mechanism for guiding the linear reciprocal movement of the scale

Chuck with position detecting function

Growing community of inventors

Tsuchiura, Japan

Satoru Ito