Toray Industries, Inc.

Kyoto University

Satoko Kanamori

Yoshinori Tanaka

Giman Jung

Hiroshi Okabe

Norihiro Takeuchi

Aiko Takayama

Michimoto Kobayashi

Yoshiharu Sakai

Yoichiro Kozaki

Hideki Sawai

Masakazu Koiwa

Takashi Mimitsuka

Atsushi Kobayashi

Shun Shimura

Masato Yanagibashi

Yuji Tanaka

Ryuichiro Hiranabe

Makoto Nishida

Kentaro Kobayashi

Keisuke Yoneda

Ryoma Miyamoto

Aya Nishio

Jihoon Cheon

Fumi Hojo

Kumiko Ogawa

Fumi Shimura

The present invention relates to a separation membrane including an organic polymer resin, in which a volume V1 of fine pores having a pore diameter of 100 nm or more is 0.3 cm/g or more and 0.5 cm/g or less, a volume V2 of fine pores having a pore diameter of less than 100 nm is 0.02 cm/g or more and less than 0.1 cm/g, and a ratio V1/V2 of the fine pore volume V1 to the fine pore volume V2 is 3 or more and 60 or less.

Separation film

The present invention provides a filter which, even when raw water is subjected to high-speed treatment, enables achieving a high solute rejection ratio and a long solute filtration life and which exhibits a low water flow resistance. The present invention pertains to a filter obtained by laminating woven fabrics or knitted fabrics, the filter being characterized in that: said woven fabrics or knitted fabrics comprise a fiber capable of adsorbing components dissolved in liquid: said fiber has a diameter of 100-600 &#x3bc;m; the woven fabrics or knitted fabrics have a porosity of 15-70%; and variation in area porosity in the thickness direction of the laminate is 15% or less.

Filter

A method of producing a chemical includes culturing cells in a culture solution in a fermentor to ferment a feedstock to produce a chemical; supplying the culture solution containing the chemical produced in the culturing to a plurality of separation membrane units arranged in parallel; filtering the culture solution supplied in the supplying to separate a permeate containing the chemical; refluxing a retentate that is not filtered in the filtering to the fermentor; and supplying a gas containing oxygen to the plurality of separation membrane units while a supply amount is changed to at least two different values to perform scrubbing, wherein the supply amount and supply time of the gas containing oxygen supplied in the culturing and the supplying the gas are set so that a kLa value is within a predetermined range from an optimal kLa value for the cells cultured in the culturing.

Method of producing chemical by continuous fermentation and continuous fermentation apparatus

A method produces a chemical through continuous fermentation including: (a) culturing a cell in a culture medium in a fermentor to ferment a feedstock to produce a chemical; (b) conducting filtration of the culture medium with a separation membrane module; (c) separating a permeate containing the chemical from the culture medium while retaining a non-permeated liquid in the fermentor, and (d) supplying a gas from at least one of a lower portion of the separation membrane module and a pipe communicating between the fermentor and the separation membrane module to adjust a gas linear velocity in the separation membrane module to 0.15 cm/s to 70 cm/s while supplying the separation membrane module with a liquid.

Method for producing chemical by continuous fermentation

An object of the present invention is to detect a human CXCL1 protein with high sensitivity. An immunoassay method is provided for a human CXCL1 protein, by which human CXCL1 or a fragment thereof in a sample is measured using two or more types of anti-human CXCL1 monoclonal antibodies or fragments thereof, wherein:

Immunoassay method for human CXCL1 protein

An object of the present invention is to realize an antibody or a fragment thereof specifically recognizing a cofilin 1 protein, and a method for detecting and testing gastrointestinal cancer with high detection performance, which comprises performing immunoassay of the cofilin 1 protein using the antibody or a fragment thereof. An immunoassay of cofilin 1 protein is characterized by measuring cofilin 1 or a fragment thereof in a sample using 2 or more types of anti-cofilin 1 monoclonal antibody or fragments thereof specifically recognizing different peptide regions in the amino acid sequence constituting the cofilin 1 protein.

Immunoassay of cofilin 1 protein

It is intended to provide a method for detecting gastric cancer, which is low invasive to a human test subject and has high detection sensitivity and accuracy. The present invention provides a method comprising measuring in vitro the amount of COTL1 protein, a variant thereof, and/or a fragment thereof in a body fluid sample derived from a human test subject, and detecting the presence or absence of gastric cancer affecting the test subject on the basis of the amount, and a kit for gastric cancer diagnosis comprising an antibody capable of specifically binding to the protein.

Marker for detecting gastric cancer and method for detecting gastric cancer

Growing community of inventors

Kanagawa, Japan

Satoko Kanamori