Kyorin Pharmaceutical Co., Ltd.

Nisshin Pharma Inc.

Satoko Fuchizawa

Toshihiro Takahashi

Makoto Yanai

Shigeru Hiramoto

Koji Kawamura

Nobuhiro Kinoshita

Masahiro Ueno

Koichi Katsuyama

This invention relates to a medicament containing as an active ingredient, a novel propanolamine having a 1,4-benzodioxane ring or a pharmaceutically acceptable salt thereof: The present compound is represented by the above formula wherein Rmay be the same or different and each represents a hydrogen atom, a halogen atom, a hydroxy group, a (C&#x2013;C)alkyl group, a (C&#x2013;C)alkoxy group, a (C&#x2013;C)alkylsulfonamido group, or a phenyl group; Reach represents a hydrogen atom or a (C&#x2013;C)alkyl group; and A represents any of a benzene ring, a pyridine ring and a pyrimidine ring. This compound is useful as a prophylactic or therapeutic agent for diabetes, obesity, hyperlipemia, depression, a respiratory disease, or a gastrointestinal disease.

Propanolamine derivative having 1, 4-benzodioxane ring

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Ohimachi, Japan

Satoko Fuchizawa