Wockhardt Limited

Wockhart Limited

Satish B Bhawsar

Mahesh Vithalbhai Patel

Prasad Keshav Deshpande

Ravindra Dattatraya Yeole

Sunil Bhaginath Jadhav

Shivaji Sampatrao Pawar

Sachin Subhash Bhagwat

Noel John De Souza

Sanjeev Joshi

Sanjay Kisan Dabhade

Vikas Vitthalrao Deshmukh

Ravikumar Tadiparthi

Vijaykumar Jagdishwar Patil

Satish Shrimant Birajdar

Amit Chandra Mishra

Nitin Shetty

Sunil Gupta

Deepak Dekhane

Mohammad Usman Shaikh

Piyush Ambalal Patel

Dilip J Upadhyay

Karuna Suresh Wankhede

Vipul Rane

Rupinder K Beri

Milind Chintaman Shukla

Shrikant V Gupte

Laxmikant Pavase

Rajesh Kale

Shivkumar Agarwal

Shiv Kumar Agarwal

Bharat Dhond

Vinod Kashinath Ahirrao

Yati Chugh

Mohammad Alam Jafri

Bharat Dond

Noel J De Souza

Habil Fakhruddin Khorakiwala

Nishith Chandra Chaturvedi

Sheela Chandrasekharan Nair

Kandepu Sreenivas

Sanjay Raikar

Mohammed Alam Jafri

Sheela Chandresekharan Nair

Mohammed A Jafri

M Madhav Reddy

Mahesh Manikrao Surwase

Shirkant V Gupte

Satish Birajdar

A process for preparation of (2S, 5R)-7-oxo-6-sulphooxy-2-[((3R)-piperidine-3-carbonyl)-hydrazino carbonyl]-1,6-diaza-bicyclo[3.2.1]octane is disclosed.

Process for preparation of (2S, 5R)-7-oxo-6-sulphooxy-2-[((3R)-piperidine-3-carbonyl)-hydrazino carbonyl]-1,6-diaza-bicyclo [3.2.1]-octane

Compounds of Formula (I), their preparation, and use in preventing or treating a bacterial infection are disclosed. (I) 

Nitrogen containing compounds and their use as antibacterial agents

A process for preparation of a compound of Formula (I) is disclosed. 

Process for preparation of (2S,5R)-6-sulphooxy-7-oxo-2-[((3R)-piperidine-3-carbonyl)-hydrazinocarbonyl]-1,6-diaza-bicyclo[3.2.1] octane

A process for preparation of (2S,5R)-7-oxo-6-sulphooxy-2-[((3R)-piperidine-3-carbonyl)-hydrazino carbonyl]-1,6-diaza-bicyclo[3.2.1]octane of Formula (I) is disclosed which is comprising reacting a compound of Formula (II) with a compound of Formula (III) to obtain a compound of Formula (IV). Crystalline compounds of Formula (I) are claimed. 

Process for preparation of (2S, 5R)-7-oxo-6-sulphooxy-2[((3R)-piperidine-3-carbonyl)-hydrazino carbonyl]-1,6-diaza-bicyclo [3.2.1]-octane

A process for preparation of (2S,5R)-7-oxo-6-sulphooxy-2-[((3R)-pyrrolidine-3-carbonyl)-hydrazino carbonyl]-1,6-diaza-bicyclo[3.2.1]octane is disclosed comprising reacting a compound of Formula (II) with a compound of Formula (III) to obtain a compound of Formula (IV). The crystalline end-product is als claimed.

Process for preparation of (2S, 5R)-7-oxo-6-sulphooxy-2-[((3R)-pyrrolidine-3-carbonyl)-hydrazino carbonyl]-1,6-diaza-bicyclo[3.2.1]octance

A process for preparation of a sodium salt of (2S,5R)-2-carboxamido-7-oxo-6-sulfooxy-1,6-diaza-bicyclo[3.2.1]octane is disclosed which is comprising the amidation of a compound of Formula (II) to obtain a compound of Formula (III). 

Process for sodium salt of (2S, 5R)-2-carboxamido-7-oxo-6-sulfooxy -1,6-diaza-bicyclo[3.2.1]octane

A process for preparation of (2S, 5R)-Sulfuric acid mono-{[(4-aminopiperidin-4-yl) carbonyl]-7-oxo-1,6-diaza-bicyclo[3.2.1]-oct-6-yl} ester is disclosed which comprises reacting a compound of Formula (II) with a compound of Formula (III) to obtain a compound of Formula (IV). 

(2S, 5R)-sulfuric acid mono-{[(4-aminopiperidin-4-yl) carbonyl]-7-oxo-1,6-diaza-bicyclo[3.2.1]-oct-6-yl} ester

Compounds of Formula (I), their preparation and use in preventing or treating bacterial infections are disclosed. 

Nitrogen containing heterocyclic compounds

Compound of Formula (I), its preparation and use in preventing or treating bacterial infection is disclosed. Formula (I) 

Nitrogen containing compounds and their use

1,6-diazabicyclo [3,2,1] octan-7-one derivatives and their use in the treatment of bacterial infections

Compounds of Formula (I), their preparation and use in preventing or treating bacterial infection is disclosed. 

Compounds are described which are efflux pump inhibitors of cellular efflux pumps of microbes. Also described are methods of preparing such compounds, methods of using such efflux pump inhibitor compounds and pharmaceutical compositions which include such compounds.

Inhibitors of cellular efflux pumps of microbes

This invention relates to new generation triple-targeting, chiral, broad-spectrum antimicrobial 7-substituted piperidino-quinolone carboxylic acid derivatives, to their optical isomers, diastereomers or enantiomers, as well as pharmaceutically acceptable salts, hydrates, prodrugs, polymorphs and pseudopolymorphs thereof, to their preparation, to their compositions and to their use.

Generation triple-targeting, chiral, broad-spectrum antimicrobial 7-substituted piperidino-quinolone carboxylic acid derivatives, their preparation, compositions and use as medicaments

The invention relates to the new arginine salt forms of S-(&minus;)-9-fluoro-6,7-dihydro-8-(4-hydroxypiperidin-1-yl)-5-methyl-1-oxo-1H,5H-benzo&lsqb;i,j&rsqb;quinolizine-2-carboxylic acid, a process for their preparation and pharmaceutical formulations which comprise those arginine salt forms as the active ingredient for its use in treating antimicrobial infections.

Chiral fluoroquinolone arginine salt forms

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Chikaltana, India

Satish B Bhawsar