Lanzatech Nz, Inc.

Sashini De Tissera

Michael Koepke

Shilpa Nagaraju

Bakir Al-Sinawi

Provided is a method of producing a product by culturing a carboxydotrophic acetogenic bacterium with a disrupting mutation in a lactate dehydrogenase enzyme in the presence of a substrate comprising CO, CO, and/or H. Preferably, the disrupting mutation reduces or eliminates the expression or activity of the enzyme such that the bacterium produces a reduced amount of lactate or no lactate.

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Skokie, IL, United States of America

Sashini De Tissera