Acelrx Pharmaceuticals, Inc.

Intuitive Surgical Operations, Inc.

The Gyrobike, Inc.

Aceirx Pharmaceuticals, Inc.

Sascha Retailleau

Andrew I Poutiatine

William Kolosi

Charles Rampersaud

Thomas A Schreck

Bruce P Edwards

Pamela Palmer

Stelios Tzannis

Edmond Chiu

Lawrence Hamel

Brian Quentin Huppi

Robert C Reid

Charles Stewart McCall

Scott Whitman

Peter E Von Behrens

Deborah Sperling

Augusta Niles

Hannah Murnen

Nathan Sigworth

Daniella Reichstetter

Eoin Brennan

In accordance with at least one embodiment of the present disclosure, a system includes an imaging instrument with a shaft including a proximal end, a distal end, and a lens at a distal end portion of the shaft. The system also includes a collar at a proximal end portion of the shaft. A cleaning device coupled to the imaging instrument includes a tubular member sized to receive the shaft of the imaging instrument. The cleaning device also includes a latching element coupled to the tubular member and configured to couple to the collar to retain the tubular member on the shaft of the imaging instrument and maintain a relative rotational relationship between the tubular member and the shaft of the imaging instrument. Devices and methods relate to cleaning devices for imaging instruments.

Cleaning devices for instruments, and related methods

Systems and methods for administration of small volume sufentanil drug dosage forms to the sublingual mucosa of a subject using a device are disclosed. The dispensing device includes a lock-out feature and a means to retard or prevent saliva and/or moisture ingress such that the drug dosage forms in the device remain dry prior to administration.

Apparatus for administering small volume oral transmucosal dosage forms

Methods and apparatus for administering small volume oral transmucosal dosage forms

Drug storage and dispensing devices for dispensing dosage forms to the oral mucosa of a patient are disclosed. The drug storage and dispensing device is a single dose applicator or a device which includes a means to retard or prevent saliva and/or moisture ingress such that the drug dosage forms in the device remain dry prior to administration.

Storage and dispensing devices for administration of oral transmucosal dosage forms

Drug storage and dispensing devices for dispensing a drug dosage form to a patient are disclosed. A cartridge includes a cartridge housing and a pusher. The cartridge housing defines a channel within which multiple tablets are disposed. The cartridge housing is configured to be removably coupled to a tablet dispensing device. A first portion of the pusher is disposed outside of the channel. A second portion of the pusher is movably disposed within the channel, and is configured to exert a force on the plurality of tablets to convey a first tablet from the channel into the tablet delivery device when the force is exerted on the first portion of the pusher.

Drug storage and dispensing devices and systems comprising the same

Methods for administering small volume oral transmucosal dosage forms using a dispensing device

Drug storage and dispensing devices for dispensing a drug dosage form are disclosed. Devices having a housing defining a nonlinear passageway and a flexible push rod to move within the nonlinear passageway are disclosed. Devices having a flexible push rod coupled to a rotation actuating member at at an end portion thereof are also disclosed.

Drug dispensing device with flexible push rod

This invention provides a stabilizing system and method for two-wheeled vehicles that affords the rider no restriction on the full range of movements (banks, leans, etc.) common to bicycles, but that provides greater stability during turns and other maneuvers so that an unintentional bank or tilt (potentially causing a fall) is less likely, even at relatively slow speeds and startup. A rotating mass of predetermined mass-value and radial mass-distribution is provided coaxially with the front axle. The mass is supported on bearings so as to freewheel with respect to the rotation of the front wheel. As such it can be induced to spin significantly faster than the front wheel thereby generating a gyroscopic effect at the front wheel about the axle. This gyroscopic effect influences the steering of the wheel by the rider. Due to precession, the wheel tends to follow any excessive bank by the vehicle, ensuring that the rider can 'steer-out-of' an unintended tilt or bank. Likewise, the gyroscopic effect limits the rider's ability to execute excessive steering, thereby preventing jackknife movements. The mass can be an electric-motor-driven flywheel within a shell housing that includes a battery, control system and drive motor. The drive motor engages a surface of the flywheel with a drive tire in a resilient manner to reduce potential damage to the motor.

System and method for providing gyroscopic stabilization to a wheeled vehicle

Growing community of inventors

San Francisco, CA, United States of America

Sascha Retailleau