Dsm Fine Chemicals Austria Nfg Gmbh & Co. Kg

Sascha Braune

Peter Poechlauer

Stefan Steinhofer

Mehul Thathagar

Bernhard Holub

Christoph Huber

Rafael Wilhelmus E G Reintjens

Nicole Theodora W Linssen

Florian Seebauer

Rafael Wilhelmus Elisabeth Ghislain Reintjens

Nicole Theodora Wilhelmina Linssen

Improved process for working up diacetone acrylamide solutions, obtained by reaction of acetone or diacetone alcohol with acrylonitrile and sulfuric acid and subsequent dilution and neutralization, in which a) the organic phase obtained subsequent to the neutralization, which comprises the crude diacetone acrylamide, is hydrolyzed by addition of an aqueous alkaline solution in order to remove acrylamide, then b) after phase separation has been carried out, the organic phase, which comprises the crude diacetone acrylamide, is neutralized by addition of an acid, and c) in succession, low-boiling-point byproducts are removed by distillation in the presence of one or more polymerization inhibitors, then t-butylacrylamide is removed by distillation and, finally, the diacetone acrylamide is isolated by product distillation, and d) the diacetone acrylamide thus obtained is converted into its final form.

Process for working up diacetone acrylamide solutions for the preparation of pure diacetone acrylamide

A process for the continuous production of a compound of Formula (II), HO&#x2014;R&#x2014;ONO(II) wherein Ris a straight chain alkyl radical having from 3 to 6 carbon atoms, in a two-phase solvent system, comprising contacting a compound of Formula (I), HO&#x2014;R&#x2014;OH (I) wherein Ris as defined above, with nitric acid in the presence of a first solvent, wherein the compound of Formula (II) is continuously extracted into a second solvent, and the reaction is carried out in a mixing microreactor which provides a power loss of at least 1.3 times the power loss provided under identical conditions by a circular cross-section straight-channel microreactor having an internal diameter equal to the average hydraulic diameter of the mixing microreactor and a length equal to the length of the mixing microreactor.

Formation of nitrate esters in microreactors and millireactors using a continuous product extraction in a turbulent flow regime

A process for the preparation of a cyclopropane derivative of Formula (I), by reacting an olefin of Formula (II), with a carbene of the formula:CRR, in a reaction vessel, optionally in the presence of a solvent, wherein, Rand Rare each independently hydrogen, C-Calkyl, C-Calkenyl, aryl, heteroaryl, heterocyclyl, carbocyclyl, heterocyclyl, &#x2014;C(O)Ror &#x2014;NR; R, R, Rand Rare each independently hydrogen, C-Calkyl, C-Calkoxy, C-Calkenyl, aryl, aryloxy, heteroaryl, heterocyclyl, carbocyclyl, heterocyclyl, &#x2014;C(O)R, &#x2014;NR, &#x2014;SR, &#x2014;S(O)R, or &#x2014;SOR, or Rand Rare as defined above and Rand Rtogether form a ring, which ring is carbocyclyl, heterocyclyl, aromatic or heteroaromatic; Ris hydrogen, hydroxy, C-Calkyl, C-Calkoxy, aryl, aryloxy, heteroaryl or &#x2014;NR; Ris hydrogen, C-Calkyl, C-Calkenyl, aryl, heteroaryl, carbocyclyl or heterocyclyl; Ris hydrogen, hydroxy, C-Calkyl, C-Calkoxy, aryl, aryloxy or heteroaryl; Ris hydrogen, C-Calkyl, C-Calkenyl, aryl, heteroaryl, carbocyclyl, heterocyclyl or C(O)R; Ris hydrogen, C-Calkyl, C-Calkenyl, aryl, heteroaryl, carbocyclyl or heterocyclyl; and Ris hydrogen, hydroxy, C-Calkyl, C-Calkoxy, aryl, or aryloxy, in the presence of copper metal or copper oxide, wherein the process is a continuous process. 

Process for the production of cyclopropane derivatives

A tube bundle falling film microreactor for performing gas-liquid reactions, which has: a) at least one vertical tube with b) a device for distributing the liquid on the inside of the tube and c) a liquid collecting system, and d) a device for gas supply and removal, and use thereof.

Tube bundle falling film microreactor for performing gas liquid reactions

Growing community of inventors

Luftenberg An der Donau, Austria

Sascha Braune