Other

Aeon Research and Technology, Inc.

Sarita Dhuper

Sunil Kumar Dhuper

Herbert Fred D'Alo

Current methods of drug administration to the lungs are inefficient. 'Endotracheal Tube with Aerosol Delivery Apparatus III' is specifically designed for uniform intrapulmonary delivery of aerosolized medication in patients on mechanical ventilation. As opposed to the current methods of drug delivery where aerosol particles are generated at the proximal end of the ETT, with majority of the particles adhering to the endotracheal tube during delivery, this invention bypasses the endotracheal tube by generating aerosol particles at its distal end. The invention consists of two coaxial hollow tubes fused to each other. The inner coaxial tube and/or one or more secondary cannulation(s) in the wall of the outer coaxial tube terminate at proximal and as MDI adapters and at the distal tip as a single or multiple micrometric orifices. The device generates one or more aerosol plumes with different geometries, velocities and orientations made possible by variations in the ID, shape, trajectory and orientation of secondary cannulation(s) and the distal orifice(s) to ensure effective aerosol delivery to respiratory system.

Endotracheal tube with feature for delivering aerosolized medication

According to one aspect of the present invention, an aerosol inhalation system including an accessory is defined by a first conduit member for delivering medication in the form of aerosol particles to a patient, as well as a first holding chamber for holding the aerosol particles prior to deliver to the first conduit member. The accessory includes a valve mechanism associated with the first conduit member and including a first valve assembly and a second valve assembly. The aerosol inhalation system includes at least one device in fluid communication with the first holding chamber for producing the aerosol particles. For example, the device can be either an MDI, a nebulizer or both devices can be used simultaneously. According to one exemplary embodiment of the present invention, the aerosol inhalation system is a closed system and is therefore capable of delivering a fixed concentration of the medication to the patient, thereby overcoming the above deficiencies that are associated with the prior art devices.

Aerosol inhalation systems and interface elements for use therein

An endotracheal tube for insertion into a patient's trachea includes a drug delivery feature and is formed of an elongated body having a proximal end for connection to a ventilator device and an opposing distal end with a bore formed therein and terminating in at least one ventilation opening. The tube also has at least one drug delivery conduit formed in the elongated body and terminating at one end with a proximal opening and at an opposite end with a distal opening. The proximal opening is adapted to be fluidly connected to a drug delivery device adapter, wherein the at least one drug delivery conduit is separated from the bore along its entire length thereof from the proximal opening to the distal opening. The distal opening is formed at the distal end of the elongated body and is located closer to the distal end than the ventilation opening.

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Old Westbury, NY, United States of America

Sarita Dhuper