The University of Toledo

Sarit B Bhaduri

Vijay K Goel

Anand K Agarwal

Dong-Shik Kim

Huan Zhou

Boren Lin

Darcy E Wagner

Sameh Saleh

Biodegradable, magnesium alloys and composites, articles produced therefrom, methods of making the same, and methods of using the same are described.

Biodegradable magnesium alloys and composites

In one aspect, there is provided a method for preparing a biocompatible coated substrate. The method generally includes: depositing nucleation amorphous calcium phosphate sites on at least a portion of an outer surface of a substrate by: exposing at least the portion of the outer surface to a mixture having a favorable Ca/P molar ratio, and irradiating with microwave energy; and, stabilizing the deposited nucleation amorphous calcium phosphate sites on the portion of the outer surface. In another aspect, there is provided herein a method for preparing a biocompatible coated substrate.

Method for modifying surfaces for better osseointegration

Compositions of, methods of making, and methods of using alkaline earth phosphate bone cements are disclosed. A bone cement composition includes a powder comprising a basic source of calcium, magnesium, or strontium, a setting solution comprising H3PO4 and a buffer, and a biocompatible polymer that is incorporated into the setting solution. The powder is mixed with the setting solution to form a bone cement paste that either (a) sets into a hardened mass, or (b) is irradiated with electromagnetic radiation to form dry powders, the dry powders then being mixed with a second setting solution to form a radiation-assisted bone cement paste that sets into a hardened mass.

Injectable, biodegradable bone cements and methods of making and using same

Compositions of, methods of making, and methods of using alkaline earth phosphate bone cements are disclosed.

Calcium phosphate nanowhisker particles, methods of making and method of using are described.

Growing community of inventors

Holland, OH, United States of America

Sarit B Bhaduri