Other

Bay Bioscience Kabushiki Kaisha

Institute for Antibodies Co., Ltd.

Kurosawa, Yoshikazu

Sari Fujiyama

Nobuhiro Takahashi

Kazuhiro Suzuki

Yoshikazu Kurosawa

Keiko Ogawa

Masahiko Kanda

Gene Kurosawa

Kazuhiro Morishita

Yoshitaka Iba

Yoshinori Ukai

Yasushi Akahori

Atsushi Sugioka

Mariko Sumitomo

Shigeaki Kato

Toshihiro Chikanishi

Masachika Azuma

Nobuhiro Hayashi

Akihiko Takasaki

Miwa Morita

Susumu Tsustumi

Kazuki Matsuda

Chiho Muramatsu

Kei Izumikawa

Masachika c/o Inst Antibodies Co Ltd Azuma

Yoshinori c/o Inst Antibodies Co Ltd Ukai

Kazuhiro Miyazaki Medical College Dept Of Biochemistry Morishita

Atsushi Viequ Court Denjiyama Sugioka

Nobuhiro c/o The Faculty Of Agriculture Takahashi

Susumu Tsutsumi

In at least one embodiment, a flow cytometer includes a flow cell defining a sheath flow encompassing a dyed biological particle, a first optical source irradiating first light onto the flow cell, a second optical source irradiating second light onto the flow cell downstream where the first light is irradiated, a first optical detector detecting scattered light or fluorescence from the biological particle to output a first electrical signal corresponding thereto, a plurality of second optical detectors arranged along the flow cell, each of the second optical detectors detecting fluorescence from the biological particle to output a second electrical signal corresponding thereto, and a signal processor summing the second electrical signals output from the plurality of the second optical detectors in a plurality of time windows estimated based upon when the first optical detector detects the scattered light or the fluorescence, thereby to increase the second electrical signals of the fluorescence from the biological particle excited by the second light.

Devices and methods for detecting and sorting biological particles in a liquid flow using substantially uniform intensity along a direction of flow of a flow cell

It is intended to clarify a molecule which is available as a target in treating or diagnosing cancer and utilize the molecule in the medical field or the research field. By treating IgSF4, which has been identified as a molecule specifically expressed in lung cancer cells, with an antibody, and ADCC activity is exerted. Based on this finding, an anti-IgSF4 antibody is provided as a means efficacious in treating cancer, etc.

Anti-IgSF4 antibody and utilization of the same

Growing community of inventors

Tokyo, Japan

Sari Fujiyama