Compugen Ltd. Corporation

Evogene Ltd.

Sarah Rachel Pollock

Osnat Sella-Tavor

Zurit Levine

Amir Toporik

Shirley Sameah-Greenwald

Michal Ayalon-Soffer

Gad S Cojocaru

Dvir Dahary

Amit Novik

Ronen Shemesh

Shira Walach

Alexander Diber

Pinchas Akiva

Rotem Sorek

Yossi Cohen

Guy Kol

Alex Diber

Maxim Shklar

Lily Bazak

Hagai Karchi

Eyal Emmanuel

Naomi Keren

Sergey Nemzer

Anat Cohen-Dayag

Galit Rotman

Merav Beiman

Assaf Wool

Avi Yeshah Rosenberg

Iris Hecht

Jeanne Bernstein

Mor Amitai

Elena Tsypkin

Michal Avalon-Soffer

Shira Wallach

Dani Eshel

Tali Handelsman

Avner Magen

Eran Halperin

Raveh Avraham Gill-More

Zipi Shaqed

Ariel Farkash

Kinneret Savitsky

Provided are isolated polynucleotides which comprise a nucleic acid sequence encoding a polypeptide which exhibits at least 94% sequence identity to SEQ ID NO: 333, and nucleic acid constructs, plants and methods of using same for increasing a yield, biomass, growth rate, vigor, oil content, abiotic stress tolerance, and/or nitrogen use efficiency of a plant.

Isolated polynucleotides and polypeptides, and methods of using same for increasing plant yield, biomass, oil content and/or growth rate

Novel splice variants, amino acid sequences and nucleotide sequences thereof, and methods of using same.

Soluble VEGFR-1 variants for diagnosis of preeclampsia

Provided are isolated polynucleotides which comprise a nucleic acid sequence at least 80% identical to SEQ ID NO: 3487, or 7; isolated polypeptides which comprise an amino acid sequence at least 80% homologous to SEQ ID NO: 246, and and methods of using same for increasing a yield, biomass, growth rate, vigor, and/or oil content, of a plant.

Isolated polynucleotides and polypeptides, and methods of using same for increasing plant yield, biomass, vigor and/or growth rate of a plant

Novel polypeptides and polynucleotides encoding same are provided. Also provided methods and pharmaceutical compositions which can be used to treat various disorders such as cancer, immunological-related, blood-related and skin-related disorders using the polypeptides and polynucleotides of the present invention. Also provided are methods and kits for diagnosing, determining predisposition and/or prognosis of various disorders using as diagnostic markers the novel polypeptides and polynucleotides of the present invention.

Polynucleotides encoding polypeptides and methods using same

Novel markers for ovarian cancer that are both sensitive and accurate. These markers are overexpressed and/or differentially expressed in ovarian cancer specifically, as opposed to normal ovarian tissue. The measurement of these markers, alone or in combination, in patient samples provides information that the diagnostician can correlate with a probable diagnosis, in ovarian cancer. The markers of the present invention, alone or in combination, show a high degree of differential detection between ovarian cancer and non-cancerous states.

Nucleotide and amino acid sequences, and assays and methods of use thereof for diagnosis of ovarian cancer

Novel splice variant nucleic acid sequences. The novel splice variants and their nucleic acid sequences according to the present invention may optionally be used for diagnosis of a variant-detectable disease as described herein.

Nucleotide and amino acid sequences, and assays and methods of use thereof for diagnosis

Novel splice variants as diagnostic markers, preferably membrane-bound. The novel variants according to the present invention may optionally be used for diagnosis of Marker-detectable disease as described herein, optionally through immunohistochemistry.

Diagnostic markers, especially for in vivo imaging and assays and methods of use thereof

Novel markers for cardiac disease that are both sensitive and accurate. These markers are differentially and/or specifically expressed in cardiac tissue, as opposed to other types of tissues, optionally and preferably including muscle tissue. The measurement of these markers, alone or in combination, in patient samples provides information that the diagnostician can correlate with a probable diagnosis of cardiac disease, including pathology and/or damage, including acute and/or chronic damage. The markers of the present invention, alone or in combination, show a high degree of differential detection between cardiac disease states and non-cardiac disease states.

Nucleotide and amino acid sequences, and assays and methods of use thereof for diagnosis of cardiac disease

Novel markers for lung cancer that are both sensitive and accurate. These markers are overexpressed in lung cancer specifically, as opposed to normal lung tissue. The measurement of these markers, alone or in combination, in patient samples provides information that the diagnostician can correlate with a probable diagnosis of lung cancer. The markers of the present invention, alone or in combination, show a high degree of differential detection between lung cancer and non-cancerous states.

Nucleotide and amino acid sequences, and assays and methods of use thereof for diagnosis of lung cancer

Novel MCP-1 splice variant polypeptides and polynucleotides encoding same are provided. Also provided are pharmaceutical compositions comprising the splice variant polypeptides and polynucleotides, vectors and host cells comprising same. The compositions of the present invention are useful to treat various MCP-1 related disorders as well as for diagnosing, determining predisposition and/or prognosis of various disorders.

MCP-1 splice variants and methods of using same

Novel markers for breast cancer that are both sensitive and accurate. These markers are overexpressed in breast cancer specifically, as opposed to normal breast tissue. The measurement of these markers, alone or in combination, in patient samples provides information that the diagnostician can correlate with a probable diagnosis of breast cancer. The markers of the present invention, alone or in combination, show a high degree of differential detection between breast cancer and non-cancerous states.

Nucleotide and amino acid sequences, and assays and methods of use thereof for diagnosis of breast cancer

Diagnostic markers, especially for in vivo imaging, and assays and methods of use thereof

Growing community of inventors

Tel Aviv, Israel

Sarah Rachel Pollock