King's College London

Leibniz Institut Fur Naturstoff-forschung Und Infektionsbiologie E.v.

Leibniz-institut Für Naturstoff-forschung Und Infektionsbiologie E.v. -hans-knöll-institut- (hki)

Sarah Hofs

Bernhard Hube

Duncan Wilson

David Moyes

Julian Naglik

Jonathan Richardson

Shirley Tang

The invention provides a peptide obtainable fromas well as variants and fragments thereof, and labelled forms of these. The peptide is immunogenic and specific binding partners for the peptide and labelled forms of these specific binding partners form a further aspect of the invention. The peptide is a fragment of the ECE1 protein and has been found to be both immunogenic and act as a pore-forming toxin. A range of therapeutic and diagnostic applications for the peptide and the specific binding partners for it form further aspects of the invention. In addition, the peptide may be used in screens for identifying compounds having useful anti-fungal activity.

Peptides and binding partners therefor

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Jena, Germany

Sarah Hofs