Dow Global Technolgoies LLC

Sarah Delaplane

Paresh C Sanghani

Christopher C Stowers

Eric C Shiue

Scott A Greenwalt

Prakash Bhosale

Genetically modified LeuCD' enzyme complexes, processes for preparing a C-C2-ketoacid utilizing genetically modified LeuCD&#x2032; enzyme complexes, and microbial organisms including modified LeuCD enzyme complexes are described. The instantly-disclosed genetically modified LeuCD&#x2032; enzyme complexes, processes for preparing a C-C2-ketoacid, and microbial organisms including modified LeuCD&#x2032; enzyme complexes can be particularly useful for producing C-Caldehydes, alkanes, alcohols, and carboxylic acids, both in vivo and in vitro.

Process to prepare elongated 2-ketoacids and C-5-C10 compounds therefrom via genetic modifications to microbial metabolic pathways

Genetically modified isopropylmalate synthases, processes for preparing a C-C2-ketoacids utilizing genetically modified isopropylmalate synthases, and microbial organisms including genetically modified isopropylmalate synthases are described. The genetically modified isopropylmalate synthases, processes for preparing a C-C2-ketoacids, and microbial organisms including genetically modified isopropylmalate synthases can be particularly useful for producing corresponding Caldehydes, alcohols, carboxylic acids, and Calkanes both in vivo and in vitro.

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Indianapolis, IN, United States of America

Sarah Delaplane