X Development LLC

The State University of New York

Sarah Ann Laszlo

Philip Edwin Watson

Gabriella Levine

Brian John Adolf

Joseph Hollis Sargent

Georgios Evangelopoulos

Phillip Yee

Vladimir Miskovic

Nina Thigpen

Bin Ni

Matthew Dixon Eisaman

Matthew Sibigtroth

Patricia Prewitt

Katherine Elise Link

Yvonne Yip

Joseph R Owens

Carl Ferman McCleary Smith

Aysja Johnson

Zhanpeng Jin

A sensor device includes a sensor housing defining a channel extending along a channel axis through the housing from a first side of the sensor housing to a second side of the sensor housing opposite the first side, at least one contact electrode extending from the first side of the housing, an electrically-conducting lead attached to the housing in electrical communication with the at least one contact electrode, and a locking mechanism located in the channel permitting one-way axial motion of a thread threaded through the channel from the first side to the second side.

Hair ratcheting electroencephalogram sensors

Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for identifying one or more regions of a brain of a biological organism that are predicted to be functionally-specialized for performing a task. In one aspect, a method comprises: obtaining data defining a synaptic connectivity graph representing synaptic connectivity between neurons in the brain of the biological organism; identifying a plurality of sub-graphs of the synaptic connectivity graph; determining, for each sub-graph of the plurality of sub-graphs, a performance measure characterizing a performance of a neural network having a neural network architecture that is specified by the sub-graph in accomplishing the task; and determining, based on the performance measures, that one or more sub-graphs of the plurality of sub-graphs correspond to regions of the brain of the biological organism that are predicted to be functionally-specialized for performing the task.

Neural functional localization using synaptic connectivity graphs

Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for training a student neural network. In one aspect, there is provided a method comprising: processing a training input using the student neural network to generate a student neural network output comprising a respective score for each of a plurality of classes; processing the training input using a brain emulation neural network to generate a brain emulation neural network output comprising a respective score for each of the plurality of classes; and adjusting current values of the student neural network parameters using gradients of an objective function that characterizes a similarity between: (i) the student neural network output for the training input, and (ii) the brain emulation neural network output for the training input.

Training artificial neural networks based on synaptic connectivity graphs

Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for training a student neural network. In one aspect, there is provided a method comprising: processing a training input using the student neural network to generate an output for the training input; processing the student neural network output using a discriminative neural network to generate a discriminative score for the student neural network output, wherein the discriminative score characterizes a prediction for whether the network input was generated using: (i) the student neural network, or (ii) a brain emulation neural network; and adjusting current values of the student neural network parameters using gradients of an objective function that depends on the discriminative score for the student neural network output.

Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for selecting a neural network architecture for performing a machine learning task. In one aspect, a method comprises: obtaining data defining a synaptic connectivity graph representing synaptic connectivity between neurons in a brain of a biological organism; generating data defining a plurality of candidate graphs based on the synaptic connectivity graph; determining, for each candidate graph, a performance measure on a machine learning task of a neural network having a neural network architecture that is specified by the candidate graph; and selecting a final neural network architecture for performing the machine learning task based on the performance measures.

Neural architecture search based on synaptic connectivity graphs

Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for generating an artificial neural network architecture based on a synaptic connectivity graph. According to one aspect, there is provided a method comprising: obtaining a synaptic resolution image of at least a portion of a brain of a biological organism; processing the image to identify: (i) a plurality of neurons in the brain, and (ii) a plurality of synaptic connections between pairs of neurons in the brain; generating data defining a graph representing synaptic connectivity between the neurons in the brain; determining an artificial neural network architecture corresponding to the graph representing the synaptic connectivity between the neurons in the brain; and processing a network input using an artificial neural network having the artificial neural network architecture to generate a network output.

Artificial neural network architectures based on synaptic connectivity graphs

Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for implementing a reservoir computing neural network. In one aspect there is provided a reservoir computing neural network comprising: (i) a brain emulation sub-network, and (ii) a prediction sub-network. The brain emulation sub-network is configured to process the network input in accordance with values of a plurality of brain emulation sub-network parameters to generate an alternative representation of the network input. The prediction sub-network is configured to process the alternative representation of the network input in accordance with values of a plurality of prediction sub-network parameters to generate the network output. The values of the brain emulation sub-network parameters are determined before the reservoir computing neural network is trained and are not adjusting during training of the reservoir computing neural network.

Reservoir computing neural networks based on synaptic connectivity graphs

Methods, systems, and computer programs encoded on a computer storage medium, for improving EEG measurements by identifying artifacts present in EEG measurements and providing a real-time indication to a user of likely artifacts in EEG measurements are described. EEG measurements of a patient can be obtained by placing a wearable device or EEG cap on a patient's head. Sensors in the cap provide EEG data to a computing device that processes the data to identify one or more artifacts in the EEG data. The artifacts can be identified by conducting one or more operations of determining the signal to noise ratio of the line noise, calculating mutual information between sensor pairs, and applying the p-welch method. Based on the types of artifacts identified, the computing device can output an indicator that provides feedback to the technician performing an EEG test to make adjustments to the test setup.

Artifact identification in EEG measurements

Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for determining an artificial neural network architecture corresponding to a sub-graph of a synaptic connectivity graph. In one aspect, there is provided a method comprising: obtaining data defining a graph representing synaptic connectivity between neurons in a brain of a biological organism; determining, for each node in the graph, a respective set of one or more node features characterizing a structure of the graph relative to the node; identifying a sub-graph of the graph, comprising selecting a proper subset of the nodes in the graph for inclusion in the sub-graph based on the node features of the nodes in the graph; and determining an artificial neural network architecture corresponding to the sub-graph of the graph.

Predicting neuron types based on synaptic connectivity graphs

Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for receiving a plurality of answers to a first set of questions. The actions include generating an adjacency matrix based on the question-answer pairs. The actions include determining a network graph that includes question nodes and edges. The actions include identifying one or more clusters of question nodes by applying a community detection algorithm on the network graph. The actions include determining, for each cluster, i) a cluster centrality and ii) a cluster magnitude. The actions include ranking the clusters based on the cluster centralities and the cluster magnitudes of the one or more clusters. The actions include selecting a second set of questions for the user. And, the actions include causing the questions from the second set of questions to be presented to the user.

Data analytic approach to personalized questionnaire developments

A method for analyzing electroencephalogram (EEG) signals is disclosed. Information associated with two or more options is presented to a user. EEG signals from a sensor coupled to the user are received contemporaneously to the user receiving information associated with the two or more options. The EEG signals are processed in real time to determine which one of the options was selected by the user. In response to determining which one of the options was selected by the user, an action from one or more possible actions associated with the information presented to the user is selected. An output associated with the selected action is then generated.

Interface for electroencephalogram for computer control

A bioamplifier for analyzing electroencephalogram (EEG) signals is disclosed. The bioamplifier includes an input terminal for receiving an EEG signal from a plurality of sensors coupled to a user. The bioamplifier also includes an analogue-to-digital converter arranged to receive the EEG signal from the input terminal and convert the EEG signal to a digital EEG signal. A data processing apparatus within the bioamplifier is arranged to receive the digital EEG signal from the analogue-to-digital converter and programmed to process, in real time the digital EEG signal using a first machine learning model to generate a cleaned EEG signal having a higher signal-to-noise ratio than the digital EEG signal. The bioamplifier further includes a power source to provide electrical power to the analogue-to-digital converter and the data processing apparatus. The bioamplifier includes a housing that contains the analogue-to-digital converter, the data processing apparatus, the power source, and the sensor input.

Electroencephalogram bioamplifier

A method for analyzing electroencephalogram (EEG) signals is disclosed. EEG signals are received from a sensor coupled to a user. Contextual information from one or both of the user and the user's environment is also received. The EEG signals are processed in real time using a machine learning model to predict an action of the user, which is associated with the contextual information. Output associated with the predicted action is then generated.

Fused electroencephalogram and machine learning for precognitive brain-computer interface for computer control

A method for obtaining an electroencephalogram (EEG) of a user is disclosed. A reference sensor is attached to the user by connecting a first component of the reference sensor to a second component of the reference sensor, at least a portion of the first component being sub-dermally implanted on or adjacent to a mastoid process of the user. At least one active sensor is attached to the user. A first signal is detected from the reference sensor simultaneously as a second signal is detected from the at least one active sensor. The EEG is obtained based on the first signal and the second signal.

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Mountain View, CA, United States of America

Sarah Ann Laszlo