George Mason Research Foundation, Inc.

Sara Sharif

Lance A Liotta

Alessandra Luchini Kunkel

Marissa A Howard

Amanda Haymond Still

Sameen Yusuf

Ngoc Bao Vuong

Kelsey Mitchell

A collapsible sample collection device with a novel, collapsible 3D capture open affinity net dispersed throughout the volume of the container, said net with tethered affinity moieties, is designed to address the need for low-cost, simple harvesting and concentration of diagnostic analytes that generally does not require any ancillary equipment. The collection device generally permits analytes of interest to be efficiently harvested from body fluid samples, in one step, concentrated, collapsed into a flat mailing size, and protected from degradation without the need for traditional cold chain technologies. The concentration factor will increase sensitivity by several orders of magnitude when coupled with any type of downstream analyte measurement, including point of care testing. The collection device, in various embodiments, obviates the need for handling transport or storage of the fluid portion of the body fluid sample (e.g. blood, urine, saliva, etc.) with a volumetric concentration factor of 5 to 100 fold. The collapsed collection device generally may be mailed to a laboratory for analysis via any chemical, immunological, electrical or other analytical methods.

Collapsible fluid collection system for point-of-care diagnostics

Growing community of inventors

Fairfax Station, VA, United States of America

Sara Sharif