Nabi Biopharmaceuticals, Inc.

Nabi

Sara E Shepherd

Ali Ibrahim Fattom

Ramesh K Sood

A majority ofandclinical isolates fall into two groups and three groups, respectively. Distinct antigens are associate with each of the five groups. Theantigens are readily obtained from strains ofand, and can elicit production of protective antibodies. Accordingly, the antigens are useful for vaccines which protect against infection by clinically significant (pathogenic)isolates. The antigens and antibodies generated to the antigens are also useful in diagnostic assays.

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A majority of and clinical isolates fall into two groups and three groups, respectively. Distinct antigens are associate with each of the five groups. The Enterococcus antigens are readily obtained from strains of and , and can elicit production of protective antibodies. Accordingly, the antigens are useful for vaccines which protect against infection by clinically significant (pathogenic) Enterococcus isolates. The antigens and antibodies generated to the antigens are also useful in diagnostic assays.

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Gaithersburg, MD, United States of America

Sara E Shepherd