Merck Patent Gmbh

Santosh Rahane

Nanying Bian

Matthew T Stone

Melissa Holstein

Daniel Scheid

Matthew Turiano

Chia-Yun Sun

Kristen Cotoni

Embodiments described herein relate to novel chromatography media for removing anti-A and/or anti-B antibodies from a sample, as well as methods of using the same. The media described herein have several advantages over previously described media including, acid and alkaline stability.

Affinity chromatography media for removal of anti-a and/or anti-b antibodies

Embodiments described herein relate to methods of evaluating quality of a chromatography media for removal of anti-A or anti-B antibodies from a sample, where the methods employ use of purified monoclonal IgM-A and IgM-B antibodies.

Methods of evaluating quality of a chromatography media which binds anti-A or anti-B antibodies

Embodiments described herein relate to methods of evaluating quality of a chromatography media for removal of anti-A or anti-B antibodies from a sample, where the methods employ use of purified Lectins.

Methods of evaluating quality of media suitable for removing anti-A or anti-B antibodies

The present invention relates to new separation materials with improved binding capacity, its manufacturing, and application, especially for binding protein A.

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Acton, MA, United States of America

Santosh Rahane