Other

Zhejiang University

Santi Tofani

Min Yang

Chao Yang

Xi Chen

Kexin Shi

Kun Zhu

Can Wang

Weizhong Gu

Shiqiang Shang

Huamei Li

Suchen Bian

Zheng Shen

Linqing Yuan

Jinhu Wang

An electromagnetic field generating apparatus for treating pathological cells, in particular with tumor suppression function. The ratio of static magnetic field to alternating magnetic field is in the range of 0.5-2.5, and the total intensity is in the range up to 100 mT. It provides non-invasive low toxicity and side effects, significantly inhibiting a plurality of tumors, influencing the intracellular superoxide radical content, and promoting cell autophagy. The mechanism of action of the magnetic field is on the electron spin energy levels and consequently on free radical concentration. Additional magnetic field having frequency up to 100 MHz and intensity down to microTesla range can be also used to improve the antitumor efficacy in combination with the static as well as the extremely low frequency electromagnetic field (1-300 Hz) influencing the spin hyperfine resonance. A combination method is also provided of a power-frequency electromagnetic field generating device and a platinum-based medicine.

Apparatus for treating pathological cells

A method and an apparatus for interfering with pathological cells survival processes, i.e. inducing directly or indirectly apoptosis, on living pathological cells, by using magnetic fields without adversely affecting normal cells. Static (S) and extremely low frequency (ELF) magnetic fields are used having low intensity comprised between 1 and 100 mT, preferably comprised between 1 and 30 mT. In particular SELF fields are used which are different sequences of S and/or ELF fields, i.e. S fields followed by ELF fields, ELF fields followed by S fields, S and ELF field together, as well as the presence of S or ELF fields alone, said ELF fields having a field frequency comprised between 1 and 1000 Hz. An apparatus for carrying out the method comprises means for generating static magnetic (S) fields crossing a working environment and/or means for generating electromagnetic extremely low frequency (ELF) fields over the working environment in addition to the S fields. Means are provided for modulating the S fields associated to the S fields generating means and varying the intensity of the S fields from 1 to 100 mT, preferably between 1 to 30 mT according to a predetermined function. Means may also be provided for modulating the ELF fields associated to the ELF fields generating means and imposing to the ELF fields a frequency between 1 and 1000 Hz with intensity comprised between 1 to 100 mT, preferably between 1 and 30 mT according to a predetermined function.

Apparatus and method for interfering with pathological cells survival processes

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Burolo, Italy

Santi Tofani