Mannkind Corporation

Integrity Bio-chemicals, LLC

Hppe, LLC

Sanket Gandhi

Ashoka V R Madduri

Matthew B Blackmon

Curtis J Rodencal

Charles R Landis

Christopher P Gardner

Jadwiga Jachowicz

Karen Moraleda

Michael Zupon

Sameer S Vhora

Charles E Milliron, Iii

Lee A Manning

Charles E Milliron

Ashoka V Madduri

Curtus J Rodencal

Ashoka VR Madduri

Loose particulate materials can be problematic in various aspects. For example, loose particulate materials may generate dust or be difficult to consolidate together. Fines in loose particulate materials may also be an issue. Coated particulates may alleviate some of the foregoing issues. Suitable coated particulates may comprise a particulate material comprising sand or a ceramic, and a polysaccharide composition coated upon the particulate material, the polysaccharide composition comprising a functionalized polysaccharide. Other particulate materials such as wood chips and animal litter particulates may be coated with functionalized polysaccharides to achieve similar advantages.

Polysaccharide compositions and particulate materials coated therewith

Reactors, reactor systems and methods for producing particles in a precipitation process are provided. The reactor includes a housing defining a reaction chamber, a stator assembly including two or more stators, a rotor assembly including two or more rotors, the rotor assembly configured for rotation about an axis of rotation relative to the stator assembly, a first inlet to supply a first reactant material to the reaction chamber at a first radial location, a second inlet to supply a second reactant material to the reaction chamber at a second radial location different from the first radial location, wherein the first and second reactant materials react to produce precipitation of particles in the reaction chamber, and an outlet to supply the particles formed in the reaction chamber.

Reactor for producing pharmaceutical particles in a precipitation process

Compositions comprising crosslinked polysaccharides, particularly levan and/or dextran, may provide advantageous benefits when admixed with concrete blends. Suitable compositions may comprise a biologically sourced surfactant, and a crosslinked polysaccharide, in which the crosslinked polysaccharide comprises at least one crosslinking group bonded via ether linkages to a first polysaccharide chain and a second polysaccharide chain. Concrete blends may comprise such compositions, a cement and water. Methods for forming and/or using the concrete blends may comprise allowing the concrete blends to form a hardened mass.

Crosslinked polysaccharide compositions and concrete blends containing the same

Polysaccharides may be partially oxidized by oxidative opening of a monosaccharide unit while still retaining glycosidic bonds. Such polysaccharides may be further functionalized with an amine moiety at a site of oxidative opening. Polysaccharides that are partially oxidized and amine-functionalized in this manner may be combined with an aqueous liquid to form compositions suitable for stabilizing clays in clay-containing formations. Clay stabilization may promote reduced swelling of the clays in the presence of water.

Compositions and methods for the stabilization of clay containing soils

The invention is directed to stabilizing functionalized polymers and compositions containing polysaccharides and polysaccharide derivatives functionalized with amine, alkyl and/or alkyl/amine moieties, and methods for reducing swelling of soils and especially clay-containing soils with stabilization functionalized polymers and compositions of the invention.

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Columbus, GA, United States of America

Sanket Gandhi