Neurowave Systems Inc.

Manning Ventures, Inc.

Sankar Barua

Tatjana Zikov

Stéphane Bibian

Duane Marhefka

Nithya Venkataraman

Nithya Venkatataman

The present invention relates to the acquisition, processing, and monitoring of signals, and particularly to the acquisition, processing, and monitoring of electrophysiological signals. More particularly, the present invention relates to the acquisition, processing, and monitoring electroencephalography (EEG) signals representing cortical/brain activity. Further, the present invention relates to a method and apparatus for acquiring such signals in the presence of electrical interference and noise. More particularly, the present invention relates to systems and methods for filtering out and rejecting electrical interference and noise while maintaining or improving the quality of the underlying physiological signal and preventing perturbation or introduction of artifacts into the physiological signal.

Physiological signal acquisition system and method with improved noise and common mode rejection performance and signal quality

The present invention relates to titration and delivery of anesthetic and sedative medications to a subject. Further, the present invention relates to a device and methods for titrating and delivering the medications in a semi-automated or fully automated manner and which can be monitored and controlled remotely. Even still further, the present invention relates to the device that can perform the titration and the delivery of the medications in a manner that minimalizes occlusion and prevents back flow of the medications. More particularly, the present invention relates to the device for the titration and the delivery of the medications using a non-concentric pumping mechanism that gradually or progressively increases and decreases occlusion in a medication delivery line within the pumping mechanism to minimize and/or prevent sudden formation and release of the occlusion in order to provide more steady and continuous flow of the medications through the device to the subject.

Intelligent pharmaceutical delivery system with non-concentric pumping mechanism to reduce flow anomaly and method of using

A system and method provides closed-loop sedation, anesthesia, or analgesia by monitoring EEG and automatically adjusting the delivery of sedative, anesthetic, and/or analgesic drugs to maintain that desired level of cortical activity for transportation or evacuation of the injured, and for closed-loop anesthesia during surgical care, and at all echelons of care.

Anesthesia and/or sedation system and method

A system and method for using electroencephalographic (EEG) signals to monitor brain function, preferably detect occurrence of traumatic brain injury (TBI) to screen, assess, and potentially provide mitigating treatment to improve short and long term adverse outcomes of mild TBI (mTBI) and TBI. The system and method provides a readily available tool to assist in accurate and objective assessment of subjects with TBI, immediately at the point of injury (POI), during transportation, or upon arrival at a care facility, that preferably is applicable without advanced training or expertise.

Field deployable brain monitor and method

The present invention relates to the titration and delivery of anesthetic and sedative medications to a subject. Further, the present invention relates to a device and methods for titrating and delivering such medications in a semi-automated or fully automated manner and which can be monitoring and controlled remotely. Even still further, the present invention relates to such a device that can perform the titration and delivery of medication in a manner that minimalizes occlusion and prevents back flow of the medication. More particularly, the present invention relates to a device for titration and delivery of medication using a non-concentric pumping mechanism that gradual or progressively increases and decreases occlusion in the medication delivery line within the pump to minimize and/or prevent sudden formation and release of occlusion in order to provide more steady and continuous flow of the medication through the device to the subject.

The invention features electronic skin including an active layer formed of bistable cholesteric liquid crystal material and articles comprising the skin, the electronic skin having uniform gray scale reflectivity. Also featured is method for producing suitable reduction pulses that will provide a display (e.g., the electronic skin) with uniform gray scale reflectivity. Reduction pulses of narrow width are used to create uniform levels of gray in the electronic skin to overcome display imperfections that cause discontinuity in the gray scale reflectivity.

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Stow, OH, United States of America

Sankar Barua