Alcon, Inc.

Aerie Pharmaceuticals, Inc.

Allergan, Inc.

Sanjib Kumar Das

Benjamin Maynor

Tomas Navratil

Thomas A Shepard

Leo Anthony Trevino

Tyler Pegoraro

Rozemarijn Verhoeven

Stuart Williams

Cheng Li

Melissa Sandahl

Janet Tully

Cheng-Wen Lin

Andres Garcia

Provided herein are pharmaceutical compositions, intravitreal implants and particle suspensions comprising a polymer matrix and at least one therapeutic agent that is released in a substantially linear manner for a particular duration.

Pharmaceutical compositions for treating ocular diseases or disorders

A medical implant is disclosed. The medical implant includes a body having a first end having a first cross-sectional dimension, a second end having a second cross-sectional dimension, and a tapered portion extending between the first end and the second end. The first cross-sectional dimension is larger than the second cross-sectional dimension. In some embodiments, the body comprises multiple layers.

Medical implant

The disclosure teaches precisely engineered biodegradable drug delivery systems and methods of making and utilizing such systems. In aspects, the biodegradable drug delivery systems taught herein comprise intravitreal ocular implants suitable for delivery of corticosteroids to the posterior segment of a human eye. The intravitreal ocular implants described herein have a desired extended drug release profile suitable for treating inflammation of the human eye.

Intravitreal drug delivery systems for the treatment of ocular conditions

Growing community of inventors

Morrisville, NC, United States of America

Sanjib Kumar Das