Sun Pharma Advanced Research Company Limited

Sanjay Nandlal Mandhane

Rajamannar Thennati

Gaurav Sanjivkumar Sheth

Gopalkumar Chimanlal Patel

Jiten Ranchhodbhai Patel

Trinadha Rao Chitturi

Chitturi Trinadha Rao

Samir Rameshchandra Shah

The present invention relates to methods of treatment of inflammatory conditions using S-[4-(3-fluoro-3-methylbutyryloxy)-but-2-ynyl]6&#x3b1;,9&#x3b1;-difluoro-17&#x3b1;-(furan-2-yl)carbonyloxy-11&#x3b2;-hydroxy-16&#x3b1;-methyl-3-oxoandrosta-1,4-diene-17&#x3b2;-carbothioate (compound of formula I), a novel anti-inflammatory compound of the androstane series and its processes of preparation. 

[object Object]

The invention provides 11&#x3b2;-hydroxyandrosta-4-ene-3-one compounds of Formula I, or physiologically acceptable salts or solvates thereof: wherein Rrepresents a moiety selected from a group consisting of (A), (B) and (C), with a proviso that when Rrepresents moiety (C), Z is S: 

11&#x3b2;-hydroxyandrosta-4-ene-3-ones

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Baroda, India

Sanjay Nandlal Mandhane