Alembic Limited

Sanjay Lakhabhai Vasoya

Rohit Ravikant Soni

Hetal Remeshchandra Shah

Ravindra Charudatta Ghotikar

Anand Kumar Pandey

The invention relates to novel compound of formula (IV), which is an organic acid salt of N-[(2'-cyanobiphenyl-4-yl)methyl]-(L)-valine ester. This compound is an useful intermediate for process of preparation of Valsartan of formula (I), chemically known as (S)-N-(1-Carboxy-2-methylprop-1-yl)-N-pentanoyl-N-[2&#x2032;-(1H-terazol-5-yl)biphenyl-4-ylmethyl]amine. This invention also relates to a process for preparing Valsartan using novel intermediate of formula (IV). 

Process for preparing valsartan

The invention relates to novel compound of formula (IV), which is an organic acid salt of N-[(2'-cyanobiphenyl-4-yl)methyl]-(L)-valine ester. This compound is an useful intermediate for process of preparation of Valsartan of formula (I), chemically known as (S)&#x2014;N-(1-Carboxy-2-methylprop-1-yl)-N-pentanoyl-N-[2&#x2032;-(1H-tetrazol-5-yl)biphenyl-4-ylmethyl]amine. This invention also relates to a process for preparing Valsartan using novel intermediate of formula (IV). 

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Vadodara, India

Sanjay Lakhabhai Vasoya