Glenmark Generics Limited

Sanjay Anantha Kale

Shekhar Bhaskar Bhirud

Nitin Sharad Chandra Pradhan

Bobba Venkata Siva Kumar

Kosampally Srinivas

Bobba Venkata Sivakumar

Chandrasekhar Batchu

A process for the preparation of strontium ranelate or a hydrate thereof is provided comprising (a) reacting a tetraester compound of Formula II: wherein R, R, R, and Rare independently a linear or branched C-Calkyl group or a substituted or unsubstituted C-Ccyclic group, in the presence of a lithium base and in a solvent with an inorganic acid salt of strontium. 

Process for the preparation of strontium ranelate

A process for preparing 5H-dibenz[b,f]azepine-5-carboxamide of the general formula: wherein R, R, Rand Rare the same or different and can be hydrogen, halogen, nitro, cyano, carboxyl, R, &#x2014;CO(R), &#x2014;OCO(R), &#x2014;O(R), &#x2014;N(R), &#x2014;CON(R), and &#x2014;COO(R), wherein R is selected from the group consisting of C-Calkyl, C-Ccycloalkyl, C-Calkenyl, C-Ccycloalkenyl, C-Calkynyl, and C-Caryl, wherein the two A groups of &#x2014;N(A)and &#x2014;CON(A)can be the same or different, and wherein Rand Rcan together form a bond is provided; the process comprising reacting 5H-dibenz[b,f]azepine of the general formula wherein R, R, Rand Rhave the aforementioned meanings, with one or more alkali or alkaline-earth cyanates and in the presence of one or more unsaturated dicarboxylic acids.

Process for the preparation of carboxamide compounds

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Navi Mumbai, India

Sanjay Anantha Kale