Hanmi Pharm. Co., Ltd.

Sangmin Yun

Eun Sook Kim

Cheol Kyung Kim

Bo Sung Kwon

Gwan Sun Lee

Kwee Hyun Suh

Kwee-Hyun Suh

Mi Young Ko

Hee Cheol Kim

Hee Seock Kim

Tae Hee Ha

Han Kyong Kim

Optically pure clopidogrel can be prepared in a high yield by optically resolving a racemic form of the compound of formula (II) using an optically active amine to form the optically active form of the compound of formula (III) or its acid-addition salt; and methylating the compound of formula (III) or its acid-addition salt.

Method preparation clopidogrel and intermediates used therein

Method of preparing clopidogrel and intermediates used therein

A crystalline clopidogrel naphthalenesulfonate or a hydrate thereof, a method for preparing same, and a pharmaceutical composition containing same are provided.

Crystalline monohydrate clopidogrel naphthalenedisulfonate and process of preparation

Ticlopidine and clopidogrel having high blood platelet aggregation inhibitory and anti-thrombotic activities are simply prepared by reacting a substituted thiophene derivative with a 2-chlorobenzylamine derivative.

Method of preparing thieno[3,2-c]pyridine derivatives and intermediates used therein

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Seongnam-si, South Korea

Sangmin Yun