Korea Advanced Institute of Science and Technology

Other

Korea Institute of Science and Technology

Yonsei University

Korea University Research and Business Foundation

Samsung Electronics Co., Ltd.

Hyundai Motor Company

Lg Chem, Ltd

Lg Electronics Inc.

Kia Motors Corporation

Kia Corporation

Industry-university Cooperation Foundation Hanyang University

Korea Research Institute of Chemical Technology

Lg Chemical Ltd.

Hanwha Chemical Corporation

Sang Yup Lee

Si Jae Park

Hyohak Song

Tae Jung Park

Tae Yong Kim

Sung Won Lim

Jin Hwan Park

Tong Un Chae

Jong Hyun Choi

Kwang Ho Lee

Dong June Ahn

Jeong Wook Lee

Yu Sin Jang

Yong Jun Choi

Jae Sung Cho

Seung Hwan Lee

Sang Woo Park

Jae-Jin Kim

So Young Yoo

Myung-Suk Chun

Ho Nam Chang

Young Koan Ko

Hee Tae Jung

Seok Jae Lee

Ki Chang Keum

Gene Lee

Seung Min Yoo

Ki Jun Jeong

Won Min Yoo

Dae Hwan Jung

Byung Hun Kim

Chan Woo Song

Nae Choon Yoo

Mee Jung Han

Young Jun Lim

Chaemyeong Lee

Cindy Pricilia Surya Prabowo

Jung Ho Ahn

Taehee Han

Min Chul Kim

Yoo Sung Ko

Junho Bang

Jong An Lee

Yu Kyung Jung

Je Woong Kim

Zhi Gang Qian

Xiaoxia Xia

Yong Kim

Jin Woo Park

Dong Young Kim

Seung Hyun Lee

Tae Wan Kim

Jae Min Park

Jin Young Lee

Seungwoo Lee

Seong M Jo

Sang Hyun Lee

Do Hyun Kim

Min Young Kim

Seung-Hwan Lee

Yang Kyu Choi

Jae Won Lee

Jong Hwa Kim

Sang Jun Lee

Dong Kwon Lim

Ji Woo Lee

Taek Ho Yang

Bong Keun Song

Hye Ok Kang

Kwang Sub Son

Eun Jeong Lee

Hyun Suk Choi

Hyun Uk Kim

Sung-Yeon Jang

Kyuboem Han

Yeon Ji Kang

Jong Moo Choi

Shi Chen

Sung Roh Yoon

Soo Yong Kang

You Jip Won

Tae Woo Lee

Jae Hyuk Cha

Min Seong Kim

Dong In Kim

Soo Yul Bae

Nam Heo

Jung Kuk Yun

Yong Ho Cho

Tae Hee Han

Hyun Cheol Chung

Hong Seok Yun

Sung Yoon Jung

Zixin Deng

Jong-il Choi

So Young Choi

Woo-Gi Lee

Pyung Cheon Lee

Jun Kyu Lee

Speaker for an automobile

Disclosed are a recombinant microorganism for producing a hydrophobic material, which is subjected to cell-membrane engineering in order to be imparted with at least one characteristic among an increase in a cell-membrane area, an increase in formation and secretion of an outer membrane vesicle, and an increase in formation of an inner membrane vesicle, and a cell-membrane engineering method for preparation thereof, whereby an insoluble hydrophobic material can be produced with high efficiency, the recombinant microorganism for high-efficiency production of carotenoids or violacein analogues is useful for producing natural pigments, antioxidants, antibiotics, cosmetic additives, anticancer agents, food additives, or nutritional supplements, and the natural pigment production technology developed herein achieves a great increase in production ability. Therefore, the present invention is effective at preparing a recombinant strain for efficient production of a variety of industrially and medically useful metabolites and at establishing an efficient preparation method.

Recombinant microorganism having increased ability to produce hydrophobic material and cell-membrane engineering method for preparation thereof

Disclosed is a method of preparing primary amines. More particularly, disclosed are a mutant microorganism transformed with a gene encoding a valine decarboxylase and a method of preparing primary amines from amino acids using the mutant microorganism. The method has an effect of synthesizing, in an environmentally friendly manner, primary amines as precursors for pharmaceuticals and agricultural chemicals using microorganisms, as an alternative to conventional chemical synthesis methods.

Method of preparing primary amines from amino acids using enzymatic conversion

The present invention relates to a recombinant microorganism imparted with increased ability to produce glutaric acid by further introducing a gene encoding a polypeptide having glutaric acid transporter activity into a microorganism having ability to produce glutaric acid, and to a method of preparing glutaric acid using the recombinant microorganism. According to the present invention, glutaric acid used for the preparation of various compounds such as polyamide, polyurethane, 1,5-pentanediol, and 5-hydroxyvaleric acid can be biosynthesized at high yield.

Recombinant microorganism transformed with a glutaric acid transporter gene and method of preparing glutaric acid using same

The present invention provides a composition for antifreezing including a gold (Au) nanostructure in which at least a portion thereof is concave, thereby it is possible to increase a survival rate of cells due to having excellent effect of inhibiting ice recrystallization when cryopreservation of the cells, and maintain a texture of food even when using in the freezing of food.

Composition for antifreezing

The present disclosure relates to a mutant microorganism in which a glycerol catabolic pathway and a 1,3-PDO biosynthetic pathway are introduced into a microorganism incapable of using glycerol as a carbon source, and a method of producing 1,3-PDO using the same. According to the present disclosure, it is possible to produce 1,3-PDO while growing a mutant microorganism having 1,3-PDO production ability by using the inexpensive raw material glycerol as a single carbon source. Thus, the present disclosure is useful for the economical production of 1,3-PDO.

Mutant microorganism having ability to produce 1,3-propanediol, and method for preparing 1,3-PDO by using same

The present invention provides a a nanostructure which includes: a core comprising one or more planes configured to come into planar contact with at least one plane of an ice crystal; and an oligopeptide which is conjugated to at least one plane of the core and comprises (Thr)-, (Ala)-, (Ser)-, or (Gly)-, wherein the nanostructure is a polyhedron-shaped nanostructure present in water in a colloidal form to control freezing, and n is an integer of 2 to 7.

Anti-freezing composition comprising gold nanoparticle with peptide

Disclosed are a mutant microorganism for producing succinic acid exhibiting improved activity of conversion of oxaloacetate to malate through the introduction of genes encoding a malate dehydrogenase, wherein an amino acid residue that interacts with a pyrophosphate moiety of NADH through an amide functional group of a main chain of malate dehydrogenase is glutamine (Gln), and a method of producing succinic acid using the same. The mutant microorganism producing succinic acid according to the present invention is capable of producing a high concentration of succinic acid at the highest productivity compared to other mutant microorganisms reported to date when the microorganism is cultured in a limited medium. In addition, the mutant microorganism is capable of producing succinic acid at higher productivity and product concentration through further advanced fermentation technology.

Mutant microorganism introduced with highly active malate dehydrogenase for producing succinic acid and method of producing succinic acid using the same

The present invention relates to a method for predicting a drug-drug interaction and a drug-food interaction by using structural information of a drug and, more particularly, to a method for predicting the mechanism of action and activity of a drug interaction through interaction prediction results expressed by a standardized sentence. When using a method for predicting a drug interaction according to the present invention, a drug interaction can be predicted quickly and accurately, and in particular, activity information of an unknown compound can also be predicted by expressing a prediction result by means of a sentence, and thus the method is very useful for developing a drug exhibiting desired activity without causing adverse effects.

Method for predicting drug-drug or drug-food interaction by using structural information of drug

Disclosed is a recombinant microorganism capable of growing using only carbon dioxide and formic acid by introducing and improving a metabolic pathway for synthesizing pyruvic acid from carbon dioxide and formic acid to enhance pyruvic acid synthesis efficiency and performing additional genetic manipulation, and a method for producing useful substances using the same. Advantageously, the recombinant microorganism is capable of synthesizing pyruvic acid, a C3 organic compound, at a remarkably improved rate, and in particular, grows well even in a medium containing only carbon dioxide and formic acid as carbon sources without a glucose supply, and is thereby capable of synthesizing pyruvic acid and various high value-added compounds using the same as an intermediate product in an economically efficient manner.

Recombinant microorganism capable of growing using only carbon dioxide and formic acid and method for producing useful substances using the recombinant microorganism

A marketing system that supports sales of goods by interlocking a customer terminal and an administrator terminal including a central server which provides an event page production tool to the administrator terminal, receives information about an event page, and transmits to the customer terminal; an administrator terminal for receiving the event page production tool from the central server to input corresponding variables to produce an event page; and a customer terminal for receiving the event page produced by the administrator terminal from the central server and inputting necessary information.

Sales support marketing system

The present invention relates to recombinanthaving 1,3-PDO productivity and reduced 3-HP productivity, and a method for producing 1,3-PDO by using same. When avariant according to the present invention is used, the productivity of 3-HP, which is a by-product, is inhibited by using low-cost glycerol as a carbon source, and thus 1,3-PDO can be produced with high efficiency.

Recombinanthaving 1,3-PDO productivity and reduced 3-HP productivity, and method for producing 1,3-PDO by using same

The present invention relates to a microorganism variant having the ability to extracellularly produce heme, and more particularly to a metabolically engineered microorganism variant having the ability to extracellularly produce heme and a method of producing heme using the same. According to the present invention, heme, an organometallic compound which is increasingly used as a health food or food supplement for the treatment of, can be extracellularly secreted and produced in high yield using the microorganism variant, but not conventional chemical synthesis or enzymatic synthesis.

Extracellular heme production method using metabolically engineered microorganism

The present invention relates to a recombinant microorganism having heterologous genes introduced thereto and a method for producing a useful material from formic acid and carbon dioxide using the microorganism. The present invention provides a novel microorganism having a cyclic metabolic pathway introduced thereto through which C3 or higher carbon organic compounds can be synthesized from formic acid and carbon dioxide, whereby carbon dioxide rich in nature and formic acid that is of low toxicity and suitable for anabolic reaction in view of reaction kinetics and which can be easily and rapidly synthesized from carbon dioxide can be used to effectively synthesize the C3 organic compound pyruvic acid from which various high-value added compound can be synthesized.

Recombinant microorganism having heterologous genes introduced thereto and method for producing useful material from formic acid and carbon dioxide using same microorganism

The present invention provides a composition comprising branched polyglycerol for controlling freezing, more specifically, the composition has a number average molecular weight of 1,000 to 20,000 g/mol and a branching of 0.1 to 1, and may control enhancement or inhibition of ice recrystallization by adjusting a content of polyglycerol.

Composition comprising branched polyglycerol for controlling freezing

Growing community of inventors

Daejeon, South Korea

Sang Yup Lee