Dongwha Pharm. Ind. Co., Ltd.

Dong Wha Pharm. Co., Ltd.

Dong Wha Pharmaceutical Ind. Co., Ltd.

Sang Wook Lee

Sang Jin Park

Yong Kyun Park

Jong Woo Kim

Hee Jeoung Park

Sung June Yoon

Nam Doo Kim

Sung Joon Yoon

Geun Hyung Lee

Hyeong Su Sim

Hwan Bong Chang

Yong Ho Chung

Dong Hyuk Sin

Je In Yoon

Jae In Yoon

Yong Huh

Hwan Bong Jang

Dong Hyuk Shin

Wang Yong Yang

Jae Jin Han

The present invention relates to novel 5-pyrimidinecarboxamide derivatives and the pharmaceutical compositions containing said derivatives, and more specifically, to 5-pyrimidinecarboxamide derivatives and their pharmacutically able salts, the process for preparing them, and the pharmaceutical compositions containing said compounds as active ingredients. In particular, said 5-pyrimidinecarboxamide derivatives of the present invention, due to their inhibitory activity against the proliferation of human immunodeficiency virus (HIV) as well as hepatitis B virus (HBV), can be used as a therapeutic agent as well as a preventive agent for hepatitis B and acquired immune deficiency syndrome (AIDS).

5-pyrimidinecarboxamide derivatives and the pharmaceutical compositions containing said derivatives

The present invention relates to novel 3-nitropyridine derivatives, pharmaceutically acceptable salts thereof and pharmaceutical compositions containing the same as active ingredients. Methods of preparing the derivatives and pharmaceutical compositions containing the same are also disclosed. The 3-nitropyridine derivatives of the present invention, due to their inhibitory activity against the proliferation of human immunodeficiency virus (HIV) as well as hepatitis B virus (HBV), can be used as therapeutic agents as well as preventive agents for hepatitis B and acquired immune deficiency syndrome (AIDS).

3-nitropyridine derivaives and the pharmaceutical compositions containing said derivatives

Anti-viral agents of formula (1) have been identified. Their preparation method is described. These 2,5-pyridinedicarboxylic acid derivatives or their pharmaceutically acceptable salts are useful in countering the proliferation of viruses such as hepatitis B virus and human immunodeficiency virus.

2,5-pyridinedicarboxylic acid derivatives

The present invention relates to novel terephthalamide derivatives and in particular to novel terephthalamide derivatives of the following formula 1, its pharmaceutically acceptable salts as antiviral agents having remarkable inhibitory actions against the proliferation of various viruses including HIV and HBV, and preparing method thereof ##STR1## wherein R.sub.1, R.sub.2 and R.sub.3 are the same as defined in the detailed description of the present invention.

Terephthalamide derivatives

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Kyunggi-do, South Korea

Sang Wook Lee