Caliper Technologies Corporation

Caliper Life Sciences, Inc.

Sang Jeong

Theo Teofanov Nikiforov

Methods, systems and assays are provided for FP detection of nucleic acid hybridization.

Detection of nucleic acid hybridization by fluorescence polarization

The present invention provides a method of assaying an enzyme-mediated coupling reaction between a first and a second reactant. The method includes contacting the first reactant with the second reactant in the presence of the enzyme. The second reactant includes a thiol derivative to yield a first product including a thiol derivative. The thiol derivative is then detected in the first product.

Homogeneous assay methods

The present invention generally provides methods for enhancing transport and direction of materials in fluidic systems, which systems utilize electroosmotic (E/O) flow systems, to affect that transport and direction. The methods generally comprise providing an effective concentration of at least one zwitterionic compound in the fluid containing the material that is to be transported or directed.

Methods and systems for enhanced fluid transport

The present invention generally provides an apparatus for enhancing transport and direction of materials in fluidic systems, which systems utilize electroosmotic (E/O) flow systems, to affect that transport and direction. The apparatus generally comprises providing an effective concentration of at least one zwitterionic compound in the fluid containing the material that is to be transported or directed.

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Mountain View, CA, United States of America

Sang Jeong