Sk Chemicals Co., Ltd.

Tiumbio Co., Ltd.

Sang-hwan Kang

Bong-Yong Lee

Keun-Ho Ryu

Jae-Sun Kim

Ju Young Lee

Hun-Taek Kim

Yong-Hyuk Kim

Hyun Jung Lee

Hyun-Jung Lee

Jung-Hoon Oh

Je Ho Ryu

Sung-hoon Park

Jung Bum Yi

Jaeseung Ahn

Dong-Chul Shin

Young Ah Shin

Euisun Park

DongChul Shin

Key-An Um

Hoechul Jung

Hoe-chul Jung

The present invention provides a novel 2-pyridyl substituted imidazole derivative, or a pharmaceutically acceptable salt or solvate thereof, which selectively inhibits the transforming growth factor-&#x3b2; (TGF-&#x3b2;) type I receptor (ALK5) and/or the activin type I receptor (ALK4); a pharmaceutical composition comprising same as an active ingredient; and a use of the 2-pyridyl substituted imidazole derivative for the manufacture of a medicament for preventing or treating a disease mediated by ALK5 and/or ALK4 receptors in a mammal.

2-pyridyl substituted imidazoles as ALK5 and/or ALK4 inhibitors

The present invention relates to a pharmaceutical or cosmetic composition and a method for promoting eyelash growth, wherein nipradilol or pharmaceutically or cosmetically acceptable salts thereof are used as active ingredients. The composition of the invention may comprise prostaglandin F2&#x3b1; analogs.

Composition for eyelash growth

2-pyridyl substituted imidazoles of the formula (I) as shown in claim, are provided, which are useful in the treatment of diseases mediated by ALK5 or ALK4 inhibitors or both.

Growing community of inventors

Suwon-si, South Korea

Sang-hwan Kang