Karo Bio Ab

Sandra Gordon

Johan Malm

Peter Brandt

Karin Edvinsson

Theresa Apelqvist

Chris Litten

Asa Hedfors

Konrad Koehler

Aiping Cheng

Lars Hagberg

Patrik Rhönnstad

Andrei Sanin

Mattias Wennerstål

Thomas Ericsson

The invention provides a compound of formula(I) or a pharmaceutically acceptable ester, amide, solvate or salt thereof, including a salt of such an ester or amide, and a solvate of such an ester, amide or salt. The invention also provides the use of such compounds in the treatment or prophylaxis of a condition associated with a disease or disorder associated with estrogen receptor activity. Formula(I) wherein R, R, R, R, R, R, R, R, Rand Rare as defined in the specification. 

Estrogen receptor ligands

This invention relates to novel compounds which are thyroid receptor ligands, preferably antagonists, and to methods for using such compounds in the treatment of cardiac and metabolic disorders, such as cardiac arrhythmias, thyrotoxicosis, subclinical hyperthyrodism and liver diseases.

Thyroid hormone receptor antagonists for cardiac and metabolic disorders II

This invention relates to novel compounds which are thyroid receptor ligands, preferably antagonists, and to methods for using such compounds in the treatment of cardiac arrhythmias, thyrotoxicosis and subclinical hyperthyrodism.

Thyroid receptor antagonists for the treatment of cardiac and metabolic disorders

Prime ring substituted thyroid receptor antagonists for the treatment of cardiac and metabolic disorders

Growing community of inventors

Mariefred, Sweden

Sandra Gordon